FORM 4 Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940

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(Print or Type Responses)

1. Name and Address of Reporting Person * Vogel Jeffrey Kenneth   2. Issuer Name and Ticker or Trading Symbol BIOSPECIFICS TECHNOLOGIES CORP [BSTC.PK] 5. Relationship of Reporting Person(s) to Issuer (Check all applicable) _____ Director __X__ 10% Owner _____ Officer (give title below) _____ Other (specify below) (Last) (First) (Middle) 1 MEADOW DRIVE 3. Date of Earliest Transaction (Month/Day/Year) 03/09/2006 (Street) LAWRENCE, NY 11559 4. If Amendment, Date Original Filed(Month/Day/Year) 6. Individual or Joint/Group Filing(Check Applicable Line) _X_ Form filed by One Reporting Person ___ Form filed by More than One Reporting Person (City) (State) (Zip) Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned

1.Title of Security (Instr. 3) 2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4) Code V Amount (A) or (D) Price Common Stock 03/09/2006   P   1,500 A $ 1.2 611,232 I See Footnote (1) Common Stock 03/09/2006   P   500 A $ 1.26 611,732 I See Footnote (2) Common Stock 03/09/2006   P   500 A $ 1.17 612,232 I See Footnote (3) Common Stock 03/10/2006   P   3,000 A $ 1.25 621,232 I See Footnote (4) Common Stock 03/13/2006   P   500 A $ 1.27 621,732 I See Footnote (5) Common Stock 03/14/2006   P   500 A $ 1.3 623,232 I See Footnote (6) Common Stock 03/15/2006   P   1,000 A $ 1.6 626,232 I See Footnote (7) Common Stock 03/16/2006   P   981 A $ 1.6 628,213 I See Footnote (8) Common Stock 03/20/2006   P   3,000 A $ 1.55 639,213 I See Footnote (9) Common Stock 03/20/2006   P   1,000 A $ 1.6 640,213 I See Footnote (10) Common Stock 03/21/2006   P   1,100 A $ 1.6 643,313 I See Footnote (11) Common Stock 03/24/2006   P   1,000 A $ 1.6 645,013 I See Footnote (12) Common Stock 03/28/2006   P   500 A $ 1.65 646,013 I See Footnote (13) Common Stock 04/03/2006   P   523 A $ 1.55 648,436 I See Footnote (14) Common Stock 04/04/2006   P   1,000 A $ 1.45 649,436 I See Footnote (15) Common Stock 04/05/2006   P   1,000 A $ 1.6 651,436 I See Footnote (16) Common Stock 10/19/2006   P   3,500 A $ 1.3 419,152 I See Footnote (17) Common Stock 10/20/2006   P   3,000 A $ 1.5 422,152 I See Footnote (18)

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
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Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)

1. Title of Derivative Security (Instr. 3)

2. Conversion or Exercise Price of Derivative Security

3. Transaction Date (Month/Day/Year)

3A. Deemed Execution Date, if any (Month/Day/Year)

4. Transaction Code (Instr. 8)

5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4, and 5)

6. Date Exercisable and Expiration Date (Month/Day/Year)

7. Title and Amount of Underlying Securities (Instr. 3 and 4)

8. Price of Derivative Security (Instr. 5)

9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)

10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4)

11. Nature of Indirect Beneficial Ownership (Instr. 4)

Code

V

(A)

(D)

Date Exercisable

Expiration Date

Title

Amount or Number of Shares

Reporting Owners

Reporting Owner Name / Address	Relationships
	Director	10% Owner	Officer	Other
Vogel Jeffrey Kenneth 1 MEADOW DRIVE LAWRENCE, NY 11559		X

Signatures

/s/ JEFFREY K. VOGEL		01/10/2007
**Signature of Reporting Person		Date

Explanation of Responses:

*	If the form is filed by more than one reporting person, see Instruction 4(b)(v).
**	Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1)	Includes (i) 104,236 common shares owned by Jeffrey K. Vogel, (ii) 295,312 common shares held by BioPartners LP (Jeffrey Vogel is the sole shareholder and president of BioManagement Inc., the sole general partner of BioPartners LP), (iii) 104,966 common shares held by his brother Jon Vogel and (iv) 106,718 common shares held by his father Sherman Vogel.
(2)	Includes (i) 104,736 common shares owned by Jeffrey K. Vogel, (ii) 295,312 common shares held by BioPartners LP (Jeffrey Vogel is the sole shareholder and president of BioManagement Inc., the sole general partner of BioPartners LP), (iii) 104,966 common shares held by his brother Jon Vogel and (iv) 106,718 common shares held by his father Sherman Vogel.
(3)	Includes (i) 105,236 common shares owned by Jeffrey K. Vogel, (ii) 295,312 common shares held by BioPartners, LP (Jeffrey Vogel is the sole shareholder and president of BioManagement Inc., the sole general partner of BioPartners LP), (iii) 104,966 common shares held by his brother, Jon Vogel and (iv) 106,718 common shares held by his father, Sherman Vogel.
(4)	Includes (i) 108,236 common shares owned by Jeffrey K. Vogel, (ii) 295,312 common shares held by BioPartners LP (Jeffrey Vogel is the sole shareholder and president of BioManagement Inc., the sole general partner of BioPartners LP), (iii) 107,966 common shares held by his brother Jon Vogel and (iv) 109,718 common shares held by his father Sherman Vogel.
(5)	Includes (i) 108,736 common shares owned by Jeffrey K. Vogel, (ii) 295,312 common shares held by BioPartners LP (Jeffrey Vogel is the sole shareholder and president of BioManagement Inc., the sole general partner of BioPartners LP), (iii) 107,966 common shares held by his brother Jon Vogel and (iv) 109,718 common shares held by his father Sherman Vogel.
(6)	Includes (i) 109,236 common shares owned by Jeffrey K. Vogel, (ii) 295,312 common shares held by BioPartners LP (Jeffrey Vogel is the sole shareholder and president of BioManagement Inc., the sole general partner of BioPartners LP), (iii) 108,466 common shares held by his brother Jon Vogel and (iv) 110,218 common shares held by his father Sherman Vogel
(7)	Includes (i) 110,236 common shares owned by Jeffrey K. Vogel, (ii) 295,312 common shares held by BioPartners LP (Jeffrey Vogel is the sole shareholder and president of BioManagement Inc., the sole general partner of BioPartners LP), (iii) 109,466 common shares held by his brother Jon Vogel and (iv) 111,218 common shares held by his father Sherman Vogel.
(8)	Includes (i) 111,217 common shares owned by Jeffrey K. Vogel, (ii) 295,312 common shares held by BioPartners LP (Jeffrey Vogel is the sole shareholder and president of BioManagement Inc., the sole general partner of BioPartners LP), (iii) 110,466 common shares held by his brother Jon Vogel and (iv) 111,218 common shares held by his father Sherman Vogel.
(9)	Includes (i) 114,217 common shares owned by Jeffrey K. Vogel, (ii) 295,312 common shares held by BioPartners LP (Jeffrey Vogel is the sole shareholder and president of BioManagement Inc., the sole general partner of BioPartners LP), (iii) 114,466 common shares held by his brother Jon Vogel and (iv) 115,218 common shares held by his father Sherman Vogel.
(10)	Includes (i) 116,317 common shares owned by Jeffrey K. Vogel, (ii) 295,312 common shares held by BioPartners LP (Jeffrey Vogel is the sole shareholder and president of BioManagement Inc., the sole general partner of BioPartners LP), (iii) 114,466 common shares held by his brother Jon Vogel and (iv) 115,218 common shares held by his father Sherman Vogel.
(11)	Includes (i) 116,317 common shares owned by Jeffrey K. Vogel, (ii) 295,312 common shares held by BioPartners LP (Jeffrey Vogel is the sole shareholder and president of BioManagement Inc., the sole general partner of BioPartners LP), (iii) 115,466 common shares held by his brother Jon Vogel and (iv) 116,218 common shares held by his father Sherman Vogel.
(12)	Includes (i) 117,317 common shares owned by Jeffrey K. Vogel, (ii) 295,312 common shares held by BioPartners LP (Jeffrey Vogel is the sole shareholder and president of BioManagement Inc., the sole general partner of BioPartners LP), (iii) 115,666 common shares held by his brother Jon Vogel and (iv) 116,718 common shares held by his father Sherman Vogel.
(13)	Includes (i) 117,817 common shares owned by Jeffrey K. Vogel, (ii) 295,312 common shares held by BioPartners LP (Jeffrey Vogel is the sole shareholder and president of BioManagement Inc., the sole general partner of BioPartners LP), (iii) 116,166 common shares held by his brother Jon Vogel and (iv) 116,718 common shares held by his father Sherman Vogel.
(14)	Includes (i) 118,340 common shares owned by Jeffrey K. Vogel, (ii) 295,312 common shares held by BioPartners LP (Jeffrey Vogel is the sole shareholder and president of BioManagement Inc., the sole general partner of BioPartners LP), (iii) 117,166 common shares held by his brother Jon Vogel and (iv) 117,618 common shares held by his father Sherman Vogel.
(15)	Includes (i) 119,340 common shares owned by Jeffrey K. Vogel, (ii) 295,312 common shares held by BioPartners LP (Jeffrey Vogel is the sole shareholder and president of BioManagement Inc., the sole general partner of BioPartners LP), (iii) 117,166 common shares held by his brother Jon Vogel and (iv) 117,618 common shares held by his father Sherman Vogel.
(16)	Includes (i) 120,340 common shares owned by Jeffrey K. Vogel, (ii) 295,312 common shares held by BioPartners LP (Jeffrey Vogel is the sole shareholder and president of BioManagement Inc., the sole general partner of BioPartners LP), (iii) 117,166 common shares held by his brother Jon Vogel and (iv) 117,618 common shares held by his father Sherman Vogel.
(17)	Includes (i) 123,840 common shares owned by Jeffrey K. Vogel and (ii) 295,312 common shares held by BioPartners LP (Jeffrey Vogel is the sole shareholder and president of BioManagement Inc., the sole general partner of BioPartners LP). As of June 14, 2006 Jeffrey Vogel had no reportable interest in the common shares held by his brother, Jon Vogel and his father, Sherman Vogel.
(18)	Includes (i) 126,840 common shares owned by Jeffrey K. Vogel and (ii) 295,312 common shares held by BioPartners LP (Jeffrey Vogel is the sole shareholder and president of BioManagement Inc., the sole general partner of BioPartners LP).

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