UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 December 27, 2005 (Date of the earliest event reported) Simulations Plus, Inc. ---------------------- (Exact name of Registrant as specified in its charter) California 001-32046 95-4595609 ---------- --------- ---------- (State or other jurisdiction (Commission File Number) (I.R.S. Employer of incorporation) Identification No.) 1220 West Avenue J, Lancaster, California 93534 ----------------------------------------------- (Address of principal executive offices) (Zip Code) (661) 723-7723 -------------- Registrant's telephone number, including area code ITEM 8.01 OTHER EVENTS. On December 27, 2005, Simulations Plus, Inc. (AMEX: SLP) announced that it has received a purchase order for the renewal of a global license for a specified number of users at six sites in the U.S., Europe, and Japan for a very large pharmaceutical company. ITEM 9.01 EXHIBITS AND REPORTS ON FORM 8-K. (a) Exhibits 99.1 Press release dated December 27, 2005 Signatures Pursuant to the requirements of the Securities Exchange Act of 1934, the Registrant has duly caused this report to be signed on its behalf by the undersigned thereunto duly authorized. SIMULATIONS PLUS, INC. Dated: December 27, 2005 By: /s/ Momoko Beran ----------------------- Momoko A. Beran Chief Financial Officer EXHIBITS INDEX -------------- Exhibit Number Description -------------- ----------- 99.1 Press release, dated December 27, 2005