PROSPECTUS                                                    FILED PURSUANT TO
                                                                 RULE 424(B)(4)
                                                     REGISTRATION NO. 333-55602


                                4,573,000 Shares

                                     [LOGO]

                                HESKA CORPORATION

                                  Common Stock

                                ________________

     This  prospectus  relates  to  the public  offering,  which  is  not  being
underwritten,  of up to 4,573,000 shares of our Common Stock which  is  held  by
some of our current stockholders.  We issued these shares of our Common Stock to
the selling stockholders identified in this prospectus in a private placement.

     The  prices  at  which  such  stockholders may  sell  the  shares  will  be
determined  by  the  prevailing market price for the  shares  or  in  negotiated
transactions.   We will not receive any of the proceeds from  the  sale  of  the
shares.

     Our  Common Stock is listed on the Nasdaq National Market under the  symbol
"HSKA." On April 4, 2001, the closing price for our Common Stock was $ 1.125 per
share.

                                ________________

     INVESTING  IN OUR COMMON STOCK INVOLVES CERTAIN RISKS.  SEE "RISK  FACTORS"
BEGINNING ON PAGE 3.

                                ________________

     THE SECURITIES AND EXCHANGE COMMISSION AND STATE SECURITIES REGULATORS HAVE
NOT APPROVED OR DISAPPROVED OF THESE SECURITIES OR DETERMINED IF THIS PROSPECTUS
IS  TRUTHFUL  OR  COMPLETE. ANY REPRESENTATION TO THE  CONTRARY  IS  A  CRIMINAL
OFFENSE.

                                ________________

                  The date of this Prospectus is April 5, 2001.

     No  person  has  been authorized to give any information  or  to  make  any
representations other than those contained in this prospectus in connection with
the   offering  made  hereby,  and  if  given  or  made,  such  information   or
representations  must  not  be relied upon as having been  authorized  by  Heska
Corporation (referred to in this prospectus as "Heska," the "Company" and "we"),
any  selling stockholder or by any other person.  Neither the delivery  of  this
prospectus  nor  any sale made hereunder shall, under any circumstances,  create
any implication that information herein is correct as of any time subsequent  to
the  date  hereof.  This prospectus does not constitute an offer to  sell  or  a
solicitation  of an offer to buy any security other than the securities  covered
by  this prospectus, nor does it constitute an offer to or solicitation  of  any
person  in any jurisdiction in which such offer or solicitation may not lawfully
be made.

                       WHERE YOU CAN FIND MORE INFORMATION

     We  file annual, quarterly and special reports, proxy statements and  other
information with the Securities and Exchange Commission.  You may read and  copy
any  document  we file at the SEC's Public Reference Rooms in Washington,  D.C.,
New  York,  New  York  and  Chicago, Illinois.  The  Public  Reference  Room  in
Washington, D.C. is located at 450 Fifth Street, N.W.  Please call the SEC at 1-
800-SEC-0330  for further information on the public conference rooms.   Our  SEC
filings  are  also  available  to  the  public  from  the  SEC's  web  site   at
http://www.sec.gov.

     The  SEC  allows us to "incorporate by reference" the information  we  file
with  them,  which means that we can disclose important information  to  you  by
referring you to those documents.  The information incorporated by reference  is
considered to be part of this prospectus, and later information filed  with  the
SEC will update and supersede this information.  We incorporate by reference the
documents  listed below and any future filings made with the SEC  under  Section
13a,  13(c),  14 or 15(d) of the Securities Exchange Act of 1934 (the  "Exchange
Act") until our offering is completed.

 (1) Heska's Annual Report on Form 10-K, for the year ended December 31, 2000;

 (2) Heska's Current Report on Form 8-K filed with the Securities and Exchange
     Commission on February 7, 2001; and

 (3) The description of our Common Stock contained in our Registration Statement
     on Form 8-A, filed with the Securities and Exchange Commission on April 24,
     1997, and any further amendment or report filed hereafter for the purpose
     of updating any such description.

     You  may  request  a  copy  of these filings, at no  cost,  by  writing  or
telephoning us at the following address:

     Heska Corporation
     1613 Prospect Parkway
     Fort Collins, Colorado 80525
     (970) 493-7272

     You  should  rely  only  on the information incorporated  by  reference  or
provided in this prospectus or the prospectus supplement.  We have authorized no
one  to  provide you with different information.  We are not making an offer  of
these securities in any state where the offer is not permitted.  You should  not
assume  that the information in this prospectus or the prospectus supplement  is
accurate as of any date other than the date on the front of the document.



                                HESKA CORPORATION

     We  discover,  develop,  manufacture and  market  companion  animal  health
products.   We  have  a  sophisticated scientific  effort  devoted  to  applying
biotechnology  to  create a broad range of diagnostic, therapeutic  and  vaccine
products  for the large and growing companion animal health market.  In addition
to  our  diagnostic, therapeutic and vaccine products, we also  sell  veterinary
diagnostic  and patient monitoring instruments and offer diagnostic services  in
the  United States and Europe to veterinarians.  Our principal executive offices
are  located  at  1613 Prospect Parkway, Fort Collins, Colorado  80525  and  our
telephone number is (970) 493-7272.

                           FORWARD-LOOKING STATEMENTS

     This  prospectus and the documents incorporated herein by reference contain
forward-looking statements within the meaning of Section 27A of  the  Securities
Act  of  1933, as amended (the "Securities Act") and Section 21E of the Exchange
Act.   Words  such as "anticipates," "expects," "intends," "plans,"  "believes,"
"seeks,"  "estimates,"  variations of such words  and  similar  expressions  are
intended to identify such forward- looking statements.  These statements are not
guarantees of future performance and are subject to certain risks, uncertainties
and  assumptions that are difficult to predict.  Therefore, actual results could
differ materially from those expressed or forecasted in any such forward-looking
statements  as a result of certain factors, including those set forth  in  "Risk
Factors,"  as  well  as  those  noted in the documents  incorporated  herein  by
reference.  In connection with forward-looking statements that appear  in  these
disclosures,  investors should carefully review the factors set  forth  in  this
prospectus under "Risk Factors."

                                  RISK FACTORS

     Our  future operating results may vary substantially from period to  period
due to a number of factors, many of which are beyond our control.  The following
discussion  highlights some of these factors and the possible  impact  of  these
factors  on  future results of operations.  You should carefully consider  these
factors  before making an investment decision.  If any of the following  factors
actually occur, our business, financial condition or results of operations could
be  harmed.  In that case, the price of our common stock could decline, and  you
could experience losses on your investment.

WE HAVE A HISTORY OF LOSSES AND MAY NEVER ACHIEVE PROFITABILITY.

     We have incurred net losses since our inception in 1988 and, as of December
31,  2000, we had an accumulated deficit of $174.5  million.  We anticipate that
we  will continue to incur additional operating losses in the near term.   These
losses  have  resulted principally from expenses incurred in  our  research  and
development programs and from general and administrative and sales and marketing
expenses.   Even if we achieve profitability, we may not be able to  sustain  or
increase profitability on a quarterly or annual basis.

WE MAY NEED ADDITIONAL CAPITAL IN THE FUTURE.

     We  have  incurred  negative cash flow from operations since  inception  in
1988.   We  do not expect to generate positive cash flow sufficient to fund  our
operations  in  the  near  term.  Moreover, based on  our  current  projections,
including  the  proceeds of our recent private placement, we may need  to  raise
additional  capital  in  the future.  If necessary,  we  expect  to  raise  this
additional capital through one or more of the following:

     *    sale of additional securities;
     *    sale of various assets;
     *    licensing of technology; and
     *    sale of various products or marketing rights.

     Additional  capital may not be available on acceptable terms,  if  at  all.
Furthermore,  any  additional  equity financing  would  likely  be  dilutive  to
stockholders,  and  additional  debt  financing,  if  available,   may   include
restrictive  covenants  which  may limit our currently  planned  operations  and
strategies.  If adequate funds are not available, we may be required to  curtail
our  operations significantly and reduce discretionary spending  to  extend  the
currently  available  cash  resources, or  to  obtain  funds  by  entering  into
collaborative agreements or other arrangements on unfavorable terms.  If we fail
to  generate adequate funding on acceptable terms when we need to, our  business
could be substantially harmed.

WE HAVE LIMITED RESOURCES TO DEVOTE TO PRODUCT DEVELOPMENT AND
COMMERCIALIZATION.  IF WE ARE NOT ABLE TO DEVOTE RESOURCES TO PRODUCT
DEVELOPMENT AND COMMERCIALIZATION, WE MAY NOT BE ABLE TO DEVELOP OUR PRODUCTS.

     Our  strategy is to develop a broad range of products addressing  companion
animal  healthcare.   We believe that our revenue growth and  profitability,  if
any, will substantially depend upon our ability to:

     *    improve market acceptance of our current products;
     *    complete development of new products; and
     *    successfully introduce and commercialize new products.

     We  have  introduced some of our products only recently  and  many  of  our
products  are  still  under development.  Because we have limited  resources  to
devote   to  product  development  and  commercialization,  any  delay  in   the
development  of one product or reallocation of resources to product  development
efforts that prove unsuccessful may delay or jeopardize the development  of  our
other product candidates.  If we fail to develop new products and bring them  to
market, our ability to generate revenues will decrease.

     In  addition, our products may not achieve satisfactory market  acceptance,
and we may not successfully commercialize them on a timely basis, or at all.  If
our products do not achieve a significant level of market acceptance, demand for
our  products will not develop as expected and it is unlikely that we ever  will
become profitable.

WE MUST OBTAIN AND MAINTAIN COSTLY REGULATORY APPROVALS IN ORDER TO MARKET OUR
PRODUCTS.

     Many  of  the  products  we  develop and market are  subject  to  extensive
regulation  by  one or more of the United States Department of  Agriculture,  or
USDA,  the  Food  and Drug Administration, or FDA, the Environmental  Protection
Agency,  or EPA, and foreign regulatory authorities.  These regulations  govern,
among  other things, the development, testing, manufacturing, labeling, storage,
premarket  approval,  advertising,  promotion,  sale  and  distribution  of  our
products.   Satisfaction of these requirements can take several years  and  time
needed to satisfy them may vary substantially, based on the type, complexity and
novelty of the product.  The effect of government regulation may be to delay  or
to  prevent marketing of our products for a considerable period of time  and  to
impose costly procedures upon our activities.  We have experienced in the  past,
and  may  experience in the future, difficulties that could delay or prevent  us
from  obtaining  the regulatory approval or license necessary  to  introduce  or
market  our  products.   Regulatory approval of our  products  may  also  impose
limitations  on  the indicated or intended uses for which our  products  may  be
marketed.

     Among  the conditions for regulatory approval is the requirement  that  our
manufacturing  facilities or those of our third party manufacturers  conform  to
current   Good   Manufacturing  Practices.   The  FDA  and  foreign   regulatory
authorities  strictly enforce Good Manufacturing Practices requirements  through
periodic inspections.  We can provide no assurance that any regulatory authority
will  determine  that our manufacturing facilities or those of our  third  party
manufacturers   will  conform  to  Good  Manufacturing  Practices  requirements.
Failure  to  comply  with  applicable  regulatory  requirements  can  result  in
sanctions  being  imposed on us or the manufacturers of our products,  including
warning  letters,  product recalls or seizures, injunctions, refusal  to  permit
products  to be imported into or exported out of the United States, refusals  of
regulatory authorities to grant approval or to allow us to enter into government
supply  contracts,  withdrawals of previously approved  marketing  applications,
civil fines and criminal prosecutions.

FACTORS BEYOND OUR CONTROL MAY CAUSE OUR OPERATING RESULTS TO FLUCTUATE, AND
SINCE MANY OF OUR EXPENSES ARE FIXED, THIS FLUCTUATION COULD CAUSE OUR STOCK
PRICE TO DECLINE.

     We  believe that our future operating results will fluctuate on a quarterly
basis due to a variety of factors, including:

     *    the introduction of new products by us or by our competitors;
     *    market acceptance of our current or new products;
     *    regulatory and other delays in product development;
     *    product recalls;
     *    competition and pricing pressures from competitive products;
     *    manufacturing delays;
     *    shipment problems;
     *    product seasonality; and
     *    changes in the mix of products sold.

     We  have high operating expenses for personnel, new product development and
marketing.  Many of these expenses are fixed in the short term.  If any  of  the
factors listed above cause our revenues to decline, our operating results  could
be substantially harmed.

     Our  operating  results in some quarters may not meet the  expectations  of
stock  market  analysts and investors.  In that case, our stock  price  probably
would decline.

WE MUST MAINTAIN VARIOUS FINANCIAL AND OTHER COVENANTS UNDER OUR REVOLVING LINE
OF CREDIT AGREEMENT.

     Under  our  revolving  line of credit agreement with Wells  Fargo  Business
Credit, Inc., we are required to comply with various financial and non-financial
covenants, and we have made various representations and warranties.   Among  the
financial covenants are requirements for monthly minimum book net worth, minimum
quarterly net income and minimum cash balances or liquidity levels.  Failure  to
comply with any of the covenants, representations or warranties would negatively
impact  our ability to borrow under the agreement.  Our inability to  borrow  to
fund our operations could materially harm our business.

A SMALL NUMBER OF LARGE CUSTOMERS ACCOUNT FOR A LARGE PERCENTAGE OF OUR
REVENUES, AND THE LOSS OF ANY OF THEM COULD HARM OUR OPERATING RESULTS.

     We currently derive a substantial portion of our revenues from sales by our
subsidiary Diamond, which manufactures various of our products and products  for
other companies in the animal health industry.  Revenues from Diamond customers,
AgriLabs  and  Bayer, comprised approximately 17% and 12% of our total  revenues
for  the  years ended December 31, 2000 and 1999, respectively.  If we  are  not
successful in maintaining our relationships with our customers and obtaining new
customers, our business and results of operations will suffer.

WE OPERATE IN A HIGHLY COMPETITIVE INDUSTRY, WHICH COULD RENDER OUR PRODUCTS
OBSOLETE OR SUBSTANTIALLY LIMIT THE VOLUME OF PRODUCTS THAT WE SELL.  THIS WOULD
LIMIT OUR ABILITY TO COMPETE AND ACHIEVE PROFITABILITY.

     We   compete   with   independent  animal  health   companies   and   major
pharmaceutical  companies that have animal health divisions.  Companies  with  a
significant  presence  in  the  animal health  market,  such  as  American  Home
Products,  Bayer, IDEXX Laboratories, Inc., Intervet International B.V.,  Merial
Ltd.,  Novartis,  Pfizer  Inc.,  Pharmacia Animal  Health  and  Schering  Plough
Corporation,  have developed or are developing products that  compete  with  our
products  or would compete with them if developed.  These competitors  may  have
substantially  greater financial, technical, research and  other  resources  and
larger,   better-established   marketing,  sales,   distribution   and   service
organizations than us.  In addition, IDEXX, which has products that compete with
our  heartworm  diagnostic  products, prohibits its  distributors  from  selling
competitors' products, including ours.  Our competitors frequently offer broader
product lines and have greater name recognition than we do.  Our competitors may
develop  or  market  technologies  or  products  that  are  more  effective   or
commercially  attractive  than our current or future  products,  or  that  would
render  our technologies and products obsolete.  Further, additional competition
could come from new entrants to the animal healthcare market.  Moreover, we  may
not have the financial resources, technical expertise or marketing, distribution
or  support  capabilities  to  compete successfully.   If  we  fail  to  compete
successfully, our ability to achieve profitability will be limited.

WE HAVE LIMITED EXPERIENCE IN MARKETING OUR PRODUCTS, AND MAY BE UNABLE TO
COMMERCIALIZE OUR PRODUCTS.

     The  market  for companion animal healthcare products is highly fragmented,
with  discount  stores  and specialty pet stores accounting  for  a  substantial
percentage of sales.  Because we sell our companion animal health products  only
to  veterinarians, we may fail to reach a substantial segment of  the  potential
market,  and  we  may  not be able to offer our products  at  prices  which  are
competitive  with  those  of companies that distribute  their  products  through
retail  channels.  We currently market our products to veterinarians  through  a
direct sales force and through third parties.  To be successful, we will have to
continue  to  develop  and train our direct sales force  or  rely  on  marketing
partnerships or other arrangements with third parties to market, distribute  and
sell  our  products.   We may not successfully develop and  maintain  marketing,
distribution  or sales capabilities, and we may not be able to make arrangements
with  third  parties to perform these activities on satisfactory terms.   If  we
fail  to  develop a successful marketing strategy, our ability to  commercialize
our products and generate revenues will decrease.

WE HAVE GRANTED THIRD PARTIES SUBSTANTIAL MARKETING RIGHTS TO OUR PRODUCTS UNDER
DEVELOPMENT.  IF OUR CURRENT THIRD PARTY MARKETING AGREEMENTS ARE NOT
SUCCESSFUL, OR IF WE ARE UNABLE TO DEVELOP OUR OWN MARKETING CAPABILITIES OR
ENTER INTO ADDITIONAL MARKETING AGREEMENTS IN THE FUTURE, WE MAY NOT BE ABLE TO
DEVELOP AND COMMERCIALIZE OUR PRODUCTS.

     Our  agreements with our corporate marketing partners generally contain  no
minimum  purchase requirements in order for them to maintain their exclusive  or
co-exclusive marketing rights.  Novartis, Eisai or Ralston Purina or  any  other
collaborative  party  may  not  devote sufficient  resources  to  marketing  our
products.   Furthermore, there is nothing to prevent Novartis, Eisai or  Ralston
Purina  or  any other collaborative party from pursuing alternative technologies
or  products  that  may compete with our products.  If we fail  to  develop  and
maintain our own marketing capabilities, we may find it necessary to continue to
rely  on  potential or actual competitors for third party marketing  assistance.
Third  party  marketing  assistance  may not  be  available  in  the  future  on
reasonable terms, if at all.  If any of these events occur, we may not  be  able
to develop and commercialize our products and our revenues will decline.

WE MAY FACE COSTLY INTELLECTUAL PROPERTY DISPUTES.

     Our  ability to compete effectively will depend in part on our  ability  to
develop and maintain proprietary aspects of our technology and either to operate
without  infringing  the proprietary rights of others or  to  obtain  rights  to
technology  owned  by third parties.  We have United States  and  foreign-issued
patents  and are currently prosecuting patent applications in the United  States
and  with  various foreign countries.  Our pending patent applications  may  not
result  in  the  issuance of any patents or that any issued patents  will  offer
protection against competitors with similar technology.  Patents we receive  may
be  challenged, invalidated or circumvented in the future or the rights  created
by those patents may not provide a competitive advantage.  We also rely on trade
secrets, technical know-how and continuing invention to develop and maintain our
competitive position.  Others may independently develop substantially equivalent
proprietary  information and techniques or otherwise gain access  to  our  trade
secrets.

     The biotechnology and pharmaceutical industries have been characterized  by
extensive litigation relating to patents and other intellectual property rights.
In 1998, Synbiotics Corporation filed a lawsuit against us alleging infringement
of  a  Synbiotics patent relating to heartworm diagnostic technology,  and  this
litigation  remains  ongoing.   We  may  become  subject  to  additional  patent
infringement  claims and litigation in the United States or other  countries  or
interference  proceedings conducted in the United States  Patent  and  Trademark
Office to determine the priority of inventions.  The defense and prosecution  of
intellectual  property suits, USPTO interference proceedings, and related  legal
and  administrative proceedings are costly, time-consuming and distracting.   We
may  also need to pursue litigation to enforce any patents issued to us  or  our
collaborative partners, to protect trade secrets or know-how owned by us or  our
collaborative partners, or to determine the enforceability, scope  and  validity
of  the proprietary rights of others.  Any litigation or interference proceeding
will  result  in  substantial  expense to us and significant  diversion  of  the
efforts of our technical and management personnel.  Any adverse determination in
litigation   or  interference  proceedings  could  subject  us  to   significant
liabilities  to  third  parties.  Further, as a result of  litigation  or  other
proceedings,  we may be required to seek licenses from third parties  which  may
not be available on commercially reasonable terms, if at all.

     We  license  technology from a number of third parties.   The  majority  of
these  license agreements impose due diligence or milestone obligations  on  us,
and  in  some cases impose minimum royalty and/or sales obligations  on  us,  in
order  for  us to maintain our rights under these agreements.  Our products  may
incorporate technologies that are the subject of patents issued to,  and  patent
applications filed by, others.  As is typical in our industry, from time to time
we  and  our collaborators have received, and may in the future receive, notices
from  third parties claiming infringement and invitations to take licenses under
third  party  patents.  It is our policy that when we receive such  notices,  we
conduct  investigations of the claims they assert.  With respect to the  notices
we  have  received to date, we believe, after due investigation,  that  we  have
meritorious  defenses  to the infringement claims asserted.   Any  legal  action
against  us or our collaborators may require us or our collaborators  to  obtain
one  or  more  licenses in order to market or manufacture affected  products  or
services.   However, we cannot assure you that we or our collaborators  will  be
able  to  obtain  licenses  for technology patented by  others  on  commercially
reasonable  terms,  that  we will be able to develop alternative  approaches  if
unable  to  obtain  licenses, or that the current and future  licenses  will  be
adequate  for  the  operation of our businesses.  Failure  to  obtain  necessary
licenses  or to identify and implement alternative approaches could  prevent  us
and  our  collaborators from commercializing our products under development  and
could substantially harm our business.

WE HAVE LIMITED MANUFACTURING EXPERIENCE AND CAPACITY AND RELY SUBSTANTIALLY ON
THIRD PARTY MANUFACTURERS.  THE LOSS OF ANY THIRD PARTY MANUFACTURERS COULD
LIMIT OUR ABILITY TO LAUNCH OUR PRODUCTS IN A TIMELY MANNER, OR AT ALL.

     To  be successful, we must manufacture, or contract for the manufacture of,
our  current and future products in compliance with regulatory requirements,  in
sufficient  quantities and on a timely basis, while maintaining product  quality
and  acceptable  manufacturing costs.  In order to  increase  our  manufacturing
capacity, we acquired Diamond in April 1996.

     We  currently rely on third parties to manufacture those products we do not
manufacture  at our Diamond facility.  We currently have supply agreements  with
Quidel  Corporation for various manufacturing services relating to our point-of-
care  diagnostic tests, with Centaq, Inc. for the manufacture of our own allergy
immunotherapy treatment products and with various manufacturers for  the  supply
of   our   veterinary  diagnostic  and  patient  monitoring  instruments.    Our
manufacturing strategy presents the following risks:


     *  Delays  in  the scale-up to quantities needed  for  product
        development could delay regulatory submissions and commercialization
        of our products in development;
     *  Our manufacturing facilities and those of some of our third party
        manufacturers are subject to ongoing periodic unannounced inspection
        by regulatory authorities, including the FDA, USDA and other federal
        and state agency's for compliance with strictly enforced Good
        Manufacturing Practices regulations and similar foreign standards, and
        we do not have control over our third party manufacturers' compliance
        with these regulations and standards;
     *  If we need to change to other commercial manufacturing
        contractors for certain of our products, additional regulatory
        licenses or approvals must be obtained for these contractors prior to
        our use.  This would require new testing and compliance inspections.
        Any new manufacturer would have to be educated in, or develop
        substantially equivalent processes necessary for the production of our
        products;
     *  If market demand for our products increases suddenly, our current
        manufacturers might not be able to fulfill our commercial needs, which
        would require us to seek new manufacturing arrangements and may result
        in substantial delays in meeting market demand; and
     *  We may not have intellectual property rights, or may have to
        share intellectual property rights, to any improvements in the
        manufacturing processes or new manufacturing processes for our
        products.

     Any of these factors could delay commercialization of our products under
development, interfere with current sales, entail higher costs and result in our
being unable to effectively sell our products.

     Our agreements with various suppliers of the veterinary medical instruments
require us to meet minimum annual sales levels to maintain our position as the
exclusive distributor of these instruments.  We may not meet these minimum sales
levels in the future, and maintain exclusivity over the distribution and sale of
these products.  If we are not the exclusive distributor of these products,
competition may increase.

WE DEPEND ON PARTNERS IN OUR RESEARCH AND DEVELOPMENT ACTIVITIES.  IF OUR
CURRENT PARTNERSHIPS AND COLLABORATIONS ARE NOT SUCCESSFUL, WE MAY NOT BE ABLE
TO DEVELOP OUR TECHNOLOGIES OR PRODUCTS.

     For various of our proposed products, we are dependent on collaborative
partners to successfully and timely perform research and development activities
on our behalf.  These collaborative partners may not complete research and
development activities on our behalf in a timely fashion, or at all.  If our
collaborative partners fail to complete research and development activities, or
fail to complete them in a timely fashion, our ability to develop technologies
and products will be impacted negatively and our revenues will decline.

WE DEPEND ON KEY PERSONNEL FOR OUR FUTURE SUCCESS.  IF WE LOSE OUR KEY PERSONNEL
OR ARE UNABLE TO ATTRACT AND RETAIN ADDITIONAL PERSONNEL, WE MAY BE UNABLE TO
ACHIEVE OUR GOALS.

     Our future success is substantially dependent on the efforts of our senior
management and scientific team.  The loss of the services of members of our
senior management or scientific staff may significantly delay or prevent the
achievement of product development and other business objectives.  Because of
the specialized scientific nature of our business, we depend substantially on
our ability to attract and retain qualified scientific and technical personnel.
There is intense competition among major pharmaceutical and chemical companies,
specialized biotechnology firms and universities and other research institutions
for qualified personnel in the areas of our activities.  If we lose the services
of, or fail to recruit, key scientific and technical personnel, the growth of
our business could be substantially impaired.

WE MAY FACE PRODUCT RETURNS AND PRODUCT LIABILITY LITIGATION AND THE EXTENT OF
OUR INSURANCE COVERAGE IS LIMITED.  IF WE BECOME SUBJECT TO PRODUCT LIABILITY
CLAIMS RESULTING FROM DEFECTS IN OUR PRODUCTS, WE MAY FAIL TO ACHIEVE MARKET
ACCEPTANCE OF OUR PRODUCTS AND OUR BUSINESS COULD BE HARMED.

     The testing, manufacturing and marketing of our current products as well as
those currently under development entail an inherent risk of product liability
claims and associated adverse publicity.  Following the introduction of a
product, adverse side effects may be discovered.  Adverse publicity regarding
such effects could affect sales of our other products for an indeterminate time
period.  To date, we have not experienced any material product liability claims,
but any claim arising in the future could substantially harm our business.
Potential product liability claims may exceed the amount of our insurance
coverage or may be excluded from coverage under the terms of the policy.  We may
not be able to continue to obtain adequate insurance at a reasonable cost, if at
all.  In the event that we are held liable for a claim against which we are not
indemnified or for damages exceeding the $10 million limits of our insurance
coverage or which results in significant adverse publicity against us, we may
lose revenue and fail to achieve market acceptance.

WE MAY BE HELD LIABLE FOR THE RELEASE OF HAZARDOUS MATERIALS, WHICH COULD RESULT
IN EXTENSIVE COSTS WHICH WOULD HARM OUR BUSINESS.

     Our products and development programs involve the controlled use of
hazardous and biohazardous materials, including chemicals, infectious disease
agents and various radioactive compounds.  Although we believe that our safety
procedures for handling and disposing of such materials comply with the
standards prescribed by applicable local, state and federal regulations, we
cannot completely eliminate the risk of accidental contamination or injury from
these materials.  In the event of such an accident, we could be held liable for
any fines, penalties, remediation costs or other damages that result.  Our
liability for the release of hazardous materials could exceed our resources,
which could lead to a shut down of our operations.  In addition, we may incur
substantial costs to comply with environmental regulations as we expand our
manufacturing capacity.

WE EXPECT TO EXPERIENCE VOLATILITY IN OUR STOCK PRICE, WHICH MAY AFFECT OUR
ABILITY TO RAISE CAPITAL IN THE FUTURE OR MAKE IT DIFFICULT FOR INVESTORS TO
SELL THEIR SHARES.

     The securities markets have from time to time experienced significant price
and volume fluctuations that are unrelated to the operating performance of
particular companies.  The market prices of securities of many publicly-held
biotechnology companies have in the past been, and can in the future be expected
to be, especially volatile.  For example, in the last twelve months our stock
price has ranged from a low of $0.59375 to a high of $4.50.  Fluctuations in the
trading price or liquidity of our common stock may adversely affect our ability
to raise capital through future equity financings.  Factors that may have a
significant impact on the market price and marketability of our common stock
include:


     *    announcements of technological innovations or new products by us
          or by our competitors;
     *    our quarterly operating results;
     *    releases of reports by securities analysts;
     *    developments or disputes concerning patents or  proprietary
          rights;
     *    regulatory developments;
     *    developments in our relationships with collaborative partners;
     *    changes in regulatory policies;
     *    litigation;
     *    economic and other external factors; and
     *    general market conditions.

     In the past, following periods of volatility in the market price of a
company's securities, securities class action litigation has often been
instituted.  If a securities class action suit is filed against us, we would
incur substantial legal fees and our management's attention and resources would
be diverted from operating our business in order to respond to the litigation.

IF WE FAIL TO MEET NASDAQ NATIONAL MARKET LISTING REQUIREMENTS, OUR COMMON STOCK
WILL BE DELISTED AND BECOME ILLIQUID.

     Our common stock is currently listed on the Nasdaq National Market.  Nasdaq
has requirements we must meet in order to remain listed on the Nasdaq National
Market.  If we continue to experience losses from our operations or we are
unable to raise additional funds, we might not be able to maintain the standards
for continued quotation on the Nasdaq National Market, including a minimum bid
price requirement of $1.00.  If the minimum bid price of our common stock were
to remain below $1.00 for 30 consecutive trading days, or if we were unable to
continue to meet Nasdaq's standards for any other reason, our common stock could
be delisted from the Nasdaq National Market.

     If as a result of the application of these listing requirements, our common
stock were delisted from the Nasdaq National Market, our stock would become
harder to buy and sell.  Further, our stock could be subject to what are known
as the "penny stock" rules.  The penny stock rules place additional requirements
on broker-dealers who sell or make a market in such securities.  Consequently,
if we were removed from the Nasdaq National Market, the ability or willingness
of broker-dealers to sell or make a market in our common stock might decline.
As a result, the ability for investors to resell shares of our common stock
could be adversely affected.

THE COMMON STOCK SOLD IN THIS OFFERING WILL INCREASE THE SUPPLY OF OUR COMMON
STOCK ON THE PUBLIC MARKET, WHICH MAY CAUSE OUR STOCK PRICE TO DECLINE.

     The sale into the public market of the common stock to be sold in this
offering could adversely affect the market price of our common stock. Most of
our  shares of common stock outstanding are eligible for immediate and
unrestricted sale in the public market at any time. Once the registration
statement of which this prospectus forms a part is declared effective, the
4,573,000 shares of common stock covered by this prospectus will be eligible for
immediate and unrestricted resale into the public market. The presence of these
additional shares of common stock in the public market may further depress our
stock price.

                                 USE OF PROCEEDS

  Heska will not receive any of the proceeds from the sale of the shares
offered by this prospectus. All proceeds from the sale of the shares offered
hereby will be for the account of the selling stockholders, as described below.
See "Selling Stockholders" and "Plan of Distribution."

                              SELLING STOCKHOLDERS

  The following table sets forth as of March 23, 2001, the name of each of the
selling stockholders, the number of shares of common stock that each selling
stockholder owns, the number of shares of common stock owned by each selling
stockholder that may be offered for sale from time to time by this prospectus,
and the number of shares of common stock to be held by each selling stockholder
assuming the sale of all the common stock offered hereby.

  Some of the selling stockholders may distribute their shares, from time to
time, to their limited and/or general partners, who may sell shares pursuant to
this prospectus. Each selling stockholder may also transfer shares owned by him
by gift, and upon any such transfer the donee would have the same right of sale
as the selling stockholder.

  The shares being offered by the selling stockholders were acquired in
connection with a private placement on February 6, 2001.  Except as set forth
below, none of the selling stockholders has had a material relationship with us
within the past three years other than as a result of the ownership of our
common stock.  We may amend or supplement this prospectus from time to time to
update the disclosure set forth herein.



                                                          SHARES BENEFICIALLY OWNED    NUMBER OF SHARES   SHARES BENEFICIALLY OWNED
                                                             PRIOR TO OFFERING(1)        BEING OFFERED       AFTER OFFERING(1)(2)
                                                          --------------------------   ----------------   -------------------------
NAME OF SELLING STOCKHOLDER                                   NUMBER        PERCENT                        NUMBER           PERCENT
---------------------------                               -------------    ---------                      ------------      -------
                                                                                                             
State of Wisconsin Investment Board (3)                     6,468,000        16.73%       1,000,000       5,468,000          14.15%
Charter Ventures II, L.P.(4).                               6,206,924        16.06%       1,000,000       5,206,924          13.47%
Lombard Odier & Cie(5)                                      2,774,200         7.18%       1,000,000       1,774,200           4.59%
Edith W. Martin, Ph.D.(6)                                      38,500             *          36,000           2,500               *
National Federation of Independent Business (NFIB) Corp       172,000             *          77,000          95,000               *
   Acct (7)
Norwalk Employees' Pension Plan (7)                           258,000             *         108,000         150,000               *
Public Employee Retirement System of Idaho (7)              1,135,000         2.94%         385,000         750,000           1.94%
City of Stamford Firemen's Pension Fund (7)                   138,000             *          38,000         100,000               *
Lazar Foundation (7)                                           63,000             *          38,000          25,000               *
Roanoke College (7)                                           138,000             *          38,000         100,000               *
HBL Charitable Unitrust (7)                                    38,000             *          38,000               -               -
Psychology Associates (7)                                      58,000             *          38,000          20,000               *
Peter Looram (7)                                               73,000             *          38,000          35,000               *
Mary C. Anderson (7)                                           77,000             *          77,000               -               *
Murray Capital, LLC (7)                                        38,000             *          38,000               -               -
The Meehan Investment Partnership I, L.P. (7)                  98,000             *          58,000          40,000               *
Domenic J. Mizio (7)                                          132,000             *          77,000          55,000               *
Theeuwes Family Trust, Felix Theeuwes Trustee (7)              77,000             *          77,000               -               -
Wells Family LLC (7)                                          231,000             *         231,000               -               -
Albert L. Zesiger (7)                                         222,000             *         115,000         107,000               *
Barrie Ramsay Zesiger (7)                                     133,000             *          58,000          75,000               *
John J. & Catherine H. Kayola (7)                               8,000             *           8,000               -               -


______________________________
*   Represents less than 1% of our common stock.
(1)  Based on 38,656,745 shares outstanding as of March 23, 2001.
(2)  Assumes that each selling stockholder sells all shares registered
     under this registration statement.  However, to our knowledge, there
     are no agreements, arrangements or understandings with respect to the
     sale  of any of our common stock, and each selling stockholder  may
     decide  not  to  sell  his shares that are  registered  under  this
     registration statement.
(3)  Based  upon  information derived from a Schedule  13G  filed  on
     February 9, 2001 by State of Wisconsin Investment Board pursuant to
     Section 13G of the Exchange Act and the rules promulgated thereunder,
     reporting its beneficial ownership of our common stock.  According to
     the Schedule 13G, State of Wisconsin Investment Board has sole power
     to  vote  and dispose of 5,468,000 shares.  Also includes 1,000,000
     shares purchased in a private placement on February 6, 2001.
(4)  Represents 3,386,510 shares and options to purchase 1,000 shares
     of our common stock held by Charter Ventures and 2,818,414 shares and
     options to purchase 1,000 shares of our common stock held by Charter
     Ventures II, L.P., with respect to which Mr. A. Barr Dolan, one of our
     directors, disclaims beneficial ownership except to the extent of his
     proportionate share therein.  Mr. Dolan is a general partner of each
     of Charter Ventures and Charter Ventures II, L.P., and may be deemed a
     beneficial owner of the shares held by such entities because of shared
     voting power with respect to such shares.
(5)  Shares listed consist of 2,755,000 shares held as custodian  for
     the Lombard Odier Nutrition Fund, over which Lombard Odier & Cie and
     Lombard Odier Fund Managers S.A. share voting and dispositive power,
     and 19,200 shares held for the benefit of private and institutional
     clients.   Such clients have the right to receive or the  power  to
     direct the receipt of dividends from, or the proceeds from the sale
     of,  such shares and retain sole voting power with respect to  such
     shares.
(6)  Dr.  Edith Martin is one of our directors.  The amount of shares
     beneficially owned includes 2,300 shares of common stock issuable upon
     exercise of stock options currency exercisable with 60 days of March
     23, 2001.
(7)  Zesiger Capital Group LLC acted as the agent and attorney-in-fact
     for  this  selling stockholder in connection with the stockholder's
     acquisition from us of the shares offered by this selling stockholder
     under  this prospectus.  Zesiger Capital Group LLC is an investment
     adviser registered with the Securities and Exchange Commission under
     the Investment Advisers Act of 1940.  This selling stockholder is an
     advisory client of Zesiger Capital Group LLC, and the shares offered
     by  this  selling stockholder under this prospectus are held  in  a
     discretionary client account managed by Zesiger Capital Group  LLC.
     Zesiger  Capital Group LLC disclaims beneficial ownership of  these
     shares.



                              PLAN OF DISTRIBUTION

  Heska is registering 4,573,000 shares of Common Stock, par value of $0.001
per share on behalf of certain selling stockholders.  Heska will receive no
proceeds from this offering. The shares may be offered by certain stockholders
of Heska or by pledgees, donees, transferees or other successors in interest
that receive such shares as a gift, partnership distribution or other non-sale
related transfer.  The shares were originally issued by Heska in connection with
the Stock Purchase Agreement between Heska and the selling stockholders, dated
February 1, 2001 (the "Stock Purchase Agreement").  The shares are being
registered by Heska pursuant to the Stock Purchase Agreement.  The shares were
issued pursuant to exemptions from the registration requirements of the
Securities Act, provided by Section 4(2) thereof.

  The selling stockholders will act independently of Heska in making decisions
with  respect to the timing, manner and size of each sale. The selling
stockholders may sell the shares on the Nasdaq National Market, or otherwise, at
prices and under terms then prevailing or at prices related to the then current
market price, at varying prices or at negotiated prices. The shares may be sold,
without limitation, by one or more of the following means of distribution: (a) a
block trade in which the broker-dealer so engaged will attempt to sell such
shares as agent, but may position and resell a portion of the block as principal
to facilitate the transaction; (b) purchases by a broker-dealer as principal and
resale by such broker-dealer for its own account pursuant to this prospectus;
(c) an over-the-counter distribution in accordance with the rules of the Nasdaq
National Market; (d) ordinary brokerage transactions and transactions in which
the broker solicits purchasers; and (e) in privately negotiated transactions. To
the extent required, this prospectus may be amended and supplemented from time
to time to describe a specific plan of distribution.

  In connection with distributions of the shares or otherwise, the selling
stockholders may enter into hedging transactions with broker-dealers or other
financial institutions. In connection with such transactions, broker-dealers or
other financial institutions may engage in short sales of the shares in the
course of hedging the positions they assume with selling stockholders. The
selling stockholders may also sell the shares short and redeliver the shares to
close out such short positions. The selling stockholders may also enter into
option or other transactions with broker-dealers or other financial institutions
which require the delivery to such broker-dealer or other financial institution
of the shares, which shares such broker-dealer or other financial institution
may resell or otherwise transfer pursuant to this prospectus (as supplemented or
amended to reflect such transaction). The selling stockholders may also pledge
the shares to a broker-dealer or other financial institution, and, upon a
default, such broker-dealer or other financial institution, may effect sales of
the pledged shares pursuant to this prospectus (as supplemented or amended to
reflect such transaction). In addition, any shares that qualify for sale
pursuant to Rule 144 may, at the option of the holder thereof, be sold under
Rule 144 rather than pursuant to this prospectus.

  Any broker-dealer participating in such transactions as agent may receive
commissions from the selling stockholders and/or purchasers of the shares (and,
if it acts as agent for the purchaser of such shares, from such purchaser).
Usual and customary brokerage fees will be paid by the selling stockholders.
Broker-dealers may agree with the selling stockholders to sell a specified
number of shares at a stipulated price per share, and, to the extent such a
broker-dealer is unable to do so acting as agent for the selling stockholders,
to purchase as principal any unsold shares at the price required to fulfill the
broker-dealer commitment to the selling stockholders. Broker-dealers who acquire
shares as principal may thereafter resell such shares from time to time in
transactions (which may involve cross and block transactions and which may
involve sales to and through other broker-dealers, including transactions of the
nature  described above) in the over-the-counter market, in negotiated
transactions or otherwise at market prices prevailing at the time of sale or at
negotiated prices, and in connection with such resales, may pay to or receive
from the purchasers of such shares commissions computed as described above.
Such broker-dealers and any other participating broker-dealers or the selling
stockholders may be deemed to be "underwriters" within the meaning of Section
2(11) of the Securities Act in connection with such sales and any such
commission, discount or concession may be deemed to be underwriting discounts or
commissions under the Securities Act.  Because the selling stockholders may be
deemed to be an underwriter under Section 2(11) of the Securities Act, the
selling stockholders will be subject to the prospectus delivery requirements of
the Securities Act.

  To comply with the securities laws of certain states, if applicable, the
shares will be sold in such jurisdictions only through registered or licensed
brokers or dealers. In addition, in certain states the shares may not be sold
unless they have been registered or qualified for sale in the applicable state
or an exemption from the registration or qualification requirement is available
and is complied with.

  Under applicable rules and regulations under the Exchange Act, any persons
engaged in the distribution of the shares may not simultaneously engage in
market making activities with respect to our common stock for a period of two
business days prior to the commencement of such distribution.  In addition and
without limiting the foregoing, each selling stockholder will be subject to
applicable provisions of the Exchange Act and the associated rules and
regulations thereunder, including, without limitation, Regulation M, which
provisions may limit the timing of purchases and sales of shares of our common
stock by the selling stockholders.  Heska will make copies of this prospectus
available to the selling stockholders and have informed them of the need for
delivery of copies of this prospectus to purchasers at or prior to the time of
any sale of the shares.  Heska assumes no obligation to so deliver copies of
this prospectus or any related prospectus supplement.

  At the time a particular offer of shares is made, if required, a prospectus
supplement will be distributed that will set forth the number of shares being
offered and the terms of the offering, including the name of any underwriter,
dealer or agent, the purchase price paid by any underwriter, any discount,
commission and other item constituting compensation, any discount, commission or
concession allowed or reallowed or paid to any dealer, and the proposed selling
price to the public.

  The selling stockholders will be responsible for any fees, disbursements and
expenses of any counsel for the selling stockholders.  All other expenses
incurred in connection with the registration of the shares, including printer's
and accounting fees and the fees, disbursements and expenses of counsel for
Heska will be borne by us up to a certain amount.  Commissions and discounts, if
any, attributable to the sales of the shares will be borne by the selling
stockholders.  The selling stockholders may agree to indemnify any broker-dealer
that participates in transactions involving sales of the shares against certain
liabilities, including liabilities arising under the Securities Act.  Heska will
indemnify the selling stockholders against claims arising out of any untrue
statement of a material fact contained in this Registration Statement or any
omission to state therein a material fact necessary in order to make the
statement made therein not misleading.

  Heska has undertaken to keep a Registration Statement of which  this
prospectus constitutes a part effective until the earlier of the disposition of
the securities offered hereby or two years measured from the effective date of
this Registration Statement.  After such period, if we choose not to maintain
the effectiveness of the Registration Statement of which this prospectus
constitutes a part, the securities issuable offered hereby may not be sold,
pledged, transferred or assigned, except in a transaction which is exempt under
the provisions of the Securities Act of pursuant to an effective registration
statement thereunder.

                                  LEGAL MATTERS

  Certain legal matters relating to the validity of the securities offered
hereby will be passed upon for Heska by Wilson Sonsini Goodrich & Rosati,
Professional Corporation, San Francisco, California.

                                     EXPERTS

     The financial statements incorporated in this prospectus by reference to
the Annual Report on Form 10-K of Heska for the year ended December 31, 2000
have been so incorporated in reliance on the report of Arthur Andersen LLP,
independent public accountants, given on the authority of said firm as experts
in giving said reports.

     PROSPECTIVE INVESTORS MAY RELY ONLY ON THE INFORMATION CONTAINED IN THIS
PROSPECTUS. NEITHER HESKA NOR ANY SELLING STOCKHOLDERS HAS AUTHORIZED ANYONE TO
PROVIDE PROSPECTIVE INVESTORS WITH INFORMATION DIFFERENT FROM THAT CONTAINED IN
THIS PROSPECTUS. THIS PROSPECTUS IS NOT AN OFFER TO SELL NOR IS IT SEEKING AN
OFFER TO BUY THE SHARES IN ANY JURISDICTION WHERE THE OFFER OR SALE IS NOT
PERMITTED. THE INFORMATION CONTAINED IN THIS PROSPECTUS IS CORRECT ONLY AS OF
THE DATE OF THIS PROSPECTUS, REGARDLESS OF THE TIME OF THE DELIVERY OF THIS
PROSPECTUS OR ANY SALE OF THE SHARES.









                                 HESKA CORPORATION

                                 4,573,000 SHARES
                                   COMMON STOCK

                                ------------------

                                    PROSPECTUS

                                ------------------



                                   April 5, 2001