Ownership Submission
FORM 4
Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940
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(Print or Type Responses)
1. Name and Address of Reporting Person *
Pacala Mark L
   2. Issuer Name and Ticker or Trading Symbol
CAREGUIDE INC [CGDE] 		5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
__X__ Director __X__ 10% Owner
_____ Officer (give title below) _____ Other (specify below)
(Last)
(First)
(Middle)
C/O ESSEX WOODLANDS HEALTH VENTURES, 21 WATERWAY AVENUE, SUITE 225		 3. Date of Earliest Transaction (Month/Day/Year)
07/25/2007
(Street)

THE WOODLANDS, TX 77380		 4. If Amendment, Date Original Filed(Month/Day/Year)
 6. Individual or Joint/Group Filing(Check Applicable Line)
___ Form filed by One Reporting Person
_X_ Form filed by More than One Reporting Person
(City)
(State)
(Zip)
Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security
(Instr. 3)		 2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code
(Instr. 8)		 4. Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5)		 5. Amount of Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 3 and 4)		 6. Ownership Form: Direct (D) or Indirect (I)
(Instr. 4)		 7. Nature of Indirect Beneficial Ownership
(Instr. 4)
Code V Amount (A) or (D) Price
Common Stock               12,413,346 I By fund (1)
Common Stock               3,476,930 I By fund (2)

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Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security
(Instr. 3)		 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (Month/Day/Year) 3A. Deemed Execution Date, if any (Month/Day/Year) 4. Transaction Code
(Instr. 8)		 5. Number of Derivative Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4, and 5)		 6. Date Exercisable and Expiration Date
(Month/Day/Year)		 7. Title and Amount of Underlying Securities
(Instr. 3 and 4)		 8. Price of Derivative Security
(Instr. 5)		 9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 4)		 10. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 4)		 11. Nature of Indirect Beneficial Ownership
(Instr. 4)
Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares
Call option equivalent (obligation to sell) $ 0 07/25/2007   E(3)     122,387 01/25/2006 07/25/2007 Common Stock 122,387 $ 0 0 I By Fund through escrow (3)
Call option equivalent (obligation to sell) $ 0 07/25/2007   E(4)     43,029 01/25/2006 07/25/2007 Common Stock 43,029 $ 0 0 I By Fund through escrow (4)

Reporting Owners

Reporting Owner Name / Address Relationships
 Director  10% Owner  Officer  Other
Pacala Mark L
C/O ESSEX WOODLANDS HEALTH VENTURES
21 WATERWAY AVENUE, SUITE 225
THE WOODLANDS, TX 77380		   X   X    
ESSEX WOODLANDS HEALTH VENTURES FUND V LP
21 WATERWAY AVENUE, SUITE 225
THE WOODLANDS, TX 77380		     X    
ESSEX WOODLANDS HEALTH VENTURES FUND IV L P
21 WATERWAY AVENUE, SUITE 225
THE WOODLANDS, TX 77380		     X    

Signatures

 /s/ Brian F. Leaf, attorney-in-fact   07/27/2007
**Signature of Reporting Person Date
 /s/ Brian F. Leaf, attorney-in-fact   07/27/2007
**Signature of Reporting Person Date
 /s/ Brian F. Leaf, attorney-in-fact   07/27/2007
**Signature of Reporting Person Date

Explanation of Responses:

* If the form is filed by more than one reporting person, see Instruction 4(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1) Shares are owned of record by Essex Woodlands Health Ventures Fund V, L.P. Mark L. Pacala, one of Issuer's directors, is a manager of entities affiliated with Essex Woodlands Health Ventures V, L.L.C, the general partner of Essex Woodlands Health Ventures Fund V, L.P., and therefore may be deemed to beneficially own the securities owned by Essex Woodlands Health Venture Fund V, L.P. Mr. Pacala disclaims beneficial ownership of the reported securities herein except to the extent of his pecuniary interest therein. The number of reported shares includes shares released from an escrow arrangement to Essex Woodlands Health Ventures Fund V, L.P. as of July 25, 2007, as described in footnote (3).
(2) Shares are owned of record by Essex Woodlands Health Ventures Fund IV, L.P. Mark L. Pacala, one of Issuer's directors, is a manager of entities affiliated with Essex Woodlands Health Ventures IV, L.L.C, the general partner of Essex Woodlands Health Ventures Fund IV, L.P., and therefore may be deemed to beneficially own the securities owned by Essex Woodlands Health Venture Fund IV, L.P. Mr. Pacala disclaims beneficial ownership of the reported securities herein except to the extent of his pecuniary interest therein. The number of reported shares includes shares released from an escrow arrangement to Essex Woodlands Health Ventures Fund IV, L.P. as of July 25, 2007, as described in footnote (4).
(3) The shares underlying this call option were previously reported by the Reporting Person on Form 4. The reported shares were held in escrow for the benefit of another stockholder of the Issuer. The release of the shares to the other stockholder was contingent upon the occurrence of certain events as described in a letter agreement between the Issuer and the other stockholder. On July 25, 2007, the escrow arrangement terminated, the call option expired in full and the underlying shares became issuable to Essex Woodlands Health Ventures Fund V, L.P.
(4) The shares underlying this call option were previously reported by the Reporting Person on Form 4. The reported shares were held in escrow for the benefit of another stockholder of the Issuer. The release of the shares to the other stockholder was contingent upon the occurrence of certain events as described in a letter agreement between the Issuer and the other stockholder. On July 25, 2007, the escrow arrangement terminated, the call option expired in full and the underlying shares became issuable to Essex Woodlands Health Ventures Fund IV, L.P.

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