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UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940 |
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Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly. | |||
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB control number. | SEC 1474 (9-02) |
1. Title of Derivative Security (Instr. 3) |
2. Conversion or Exercise Price of Derivative Security | 3. Transaction Date (Month/Day/Year) | 3A. Deemed Execution Date, if any (Month/Day/Year) | 4. Transaction Code (Instr. 8) |
5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4, and 5) |
6. Date Exercisable and Expiration Date (Month/Day/Year) |
7. Title and Amount of Underlying Securities (Instr. 3 and 4) |
8. Price of Derivative Security (Instr. 5) |
9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) |
10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4) |
11. Nature of Indirect Beneficial Ownership (Instr. 4) |
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Code | V | (A) | (D) | Date Exercisable | Expiration Date | Title | Amount or Number of Shares |
Reporting Owner Name / Address | Relationships | |||
Director | 10% Owner | Officer | Other | |
MPM BIOVENTURES II QP LP C/O MPM ASSET MANAGEMENT 200 CLARENDON STREET BOSTON, MA 02116 |
X | |||
MPM BIOVENTURES II LP C/O MPM ASSET MANAGEMENT 200 CLARENDON STREET BOSTON, MA 02116 |
X | |||
MPM BIOVENTURES GMBH & CO PARALLEL BETEILIGUNGS KG C/O MPM ASSET MANAGEMENT 200 CLARENDON STREET BOSTON, MA 02116 |
X | |||
MPM ASSET MANAGEMENT INVESTORS 2000B LLC C/O MPM ASSET MANAGEMENT 200 CLARENDON STREET BOSTON, MA 02116 |
X | |||
MPM ASSET MANAGEMENT II LP C/O MPM ASSET MANAGEMENT 200 CLARENDON STREET BOSTON, MA 02116 |
X | |||
MPM ASSET MANAGEMENT II LLC C/O MPM ASSET MANAGEMENT 200 CLARENDON STREET BOSTON, MA 02116 |
X | |||
GADICKE ANSBERT C/O MPM ASSET MANAGEMENT 200 CLARENDON STREET BOSTON, MA 02116 |
X | |||
STEINMETZ MICHAEL C/O MPM ASSET MANAGEMENT 200 CLARENDON STREET BOSTON, MA 02116 |
X | |||
EVNIN LUKE C/O MPM ASSET MANAGEMENT 200 CLARENDON STREET BOSTON, MA 02116 |
X | |||
GALAKATOS NICHOLAS C/O MPM ASSET MANAGEMENT 200 CLARENDON STREET BOSTON, MA 02116 |
X |
By Luke Evnin, investment manager of MPM Asset Management II LLC, the general partner of MPM Asset Management II, L.P., the general partner of MPM BioVentures II-QP, L.P. /s/ Luke Evnin | 05/30/2008 | |
**Signature of Reporting Person | Date | |
By Luke Evnin, investment manager of MPM Asset Management II LLC, the general partner of MPM Asset Management II, L.P., the general partner of MPM BioVentures II, L.P. /s/ Luke Evnin | 05/30/2008 | |
**Signature of Reporting Person | Date | |
By Luke Evnin, investment manager of MPM Asset Management II LLC, the general partner of MPM Asset Management II, L.P., the special limited partner of MPM BioVentures GmbH and Co. Parallel-Beteiligungs KG /s/ Luke Evnin | 05/30/2008 | |
**Signature of Reporting Person | Date | |
By Luke Evnin, investment manager of MPM Asset Management Investors 2000B LLC /s/ Luke Evnin | 05/30/2008 | |
**Signature of Reporting Person | Date | |
By Luke Evnin, investment manager of MPM Asset Management II LLC, the general partner of MPM Asset Management II, L.P. /s/ Luke Evnin | 05/30/2008 | |
**Signature of Reporting Person | Date | |
By Luke Evnin, investment manager of MPM Asset Management II, LLC /s/ Luke Evnin | 05/30/2008 | |
**Signature of Reporting Person | Date | |
/s/ Ansbert Gadicke | 05/30/2008 | |
**Signature of Reporting Person | Date | |
/s/ Michael Steinmetz | 05/30/2008 | |
**Signature of Reporting Person | Date | |
/s/ Luke Evnin | 05/30/2008 | |
**Signature of Reporting Person | Date | |
/s/ Nicholas Galakatos | 05/30/2008 | |
**Signature of Reporting Person | Date |
* | If the form is filed by more than one reporting person, see Instruction 4(b)(v). |
** | Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a). |
(1) | The shares were held as follows: 2,038,512 by MPM BioVentures II-QP, L.P. ("BV II QP"), 224,984 by MPM BioVentures II, L.P. ("BV II"), 46,930 by MPM Asset Management Investors 2000B LLC ("AM 2000") and 717,656 by MPM BioVentures GmbH & Co. Parallel-Beteiligungs KG ("BV KG"). MPM Asset Management II, L.P. and MPM Asset Management II LLC ("AM II LLC") are the direct and indirect general partners of BV II QP, BV II and BV KG. Luke Evnin, Ansbert Gadicke, Nicholas Galakatos, Michael Steinmetz and Kurt Wheeler (who is a director of the issuer and files Section 16 reports separately) are the members of AM II LLC and AM 2000. Each of the filing persons disclaims beneficial ownership of the securities except to the extent of his or its respective pecuniary interest therein. |