FORM 4 Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940

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(Print or Type Responses)

1. Name and Address of Reporting Person * COZADD BRUCE C   2. Issuer Name and Ticker or Trading Symbol Jazz Pharmaceuticals plc [JAZZ] 5. Relationship of Reporting Person(s) to Issuer (Check all applicable) __X__ Director _____ 10% Owner __X__ Officer (give title below) _____ Other (specify below) Chairman and CEO (Last) (First) (Middle) C/O JAZZ PHARMACEUTICALS PLC, CONNAUGHT HOUSE, 1 BURLINGTON RD, FL. 4 3. Date of Earliest Transaction (Month/Day/Year) 03/21/2013 (Street) DUBLIN 4, L2  4. If Amendment, Date Original Filed(Month/Day/Year) 6. Individual or Joint/Group Filing(Check Applicable Line) _X_ Form filed by One Reporting Person ___ Form filed by More than One Reporting Person (City) (State) (Zip) Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned

1.Title of Security (Instr. 3) 2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4) Code V Amount (A) or (D) Price Ordinary Shares 03/21/2013   M   15,902 A $ 15.09 638,063 D   Ordinary Shares 03/21/2013   M   5,299 A $ 30.18 643,362 D   Ordinary Shares 03/21/2013   M   5,299 A $ 45.27 648,661 D   Ordinary Shares 03/21/2013   M   12,583 A $ 19.37 661,244 D   Ordinary Shares 03/21/2013   M   7,040 A $ 7.96 668,284 D   Ordinary Shares 03/21/2013   M   182 A $ 1.25 668,466 D   Ordinary Shares 03/21/2013   M   2,177 A $ 11.48 670,643 D

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Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)

1. Title of Derivative Security (Instr. 3)	2. Conversion or Exercise Price of Derivative Security	3. Transaction Date (Month/Day/Year)	3A. Deemed Execution Date, if any (Month/Day/Year)	4. Transaction Code (Instr. 8)		5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4, and 5)		6. Date Exercisable and Expiration Date (Month/Day/Year)		7. Title and Amount of Underlying Securities (Instr. 3 and 4)		8. Price of Derivative Security (Instr. 5)	9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)	10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4)	11. Nature of Indirect Beneficial Ownership (Instr. 4)
				Code	V	(A)	(D)	Date Exercisable	Expiration Date	Title	Amount or Number of Shares
Incentive Stock Option (right to buy)	$ 15.09	03/21/2013		M			15,902	(1)	02/17/2014	Ordinary Shares	15,902	$ 0	0	D
Incentive Stock Option (right to buy)	$ 30.18	03/21/2013		M			5,299	(1)	02/17/2014	Ordinary Shares	5,299	$ 0	0	D
Incentive Stock Option (right to buy)	$ 45.27	03/21/2013		M			5,299	(1)	02/17/2014	Ordinary Shares	5,299	$ 0	0	D
Incentive Stock Option (right to buy)	$ 19.37	03/21/2013		M			12,583	(2)	02/26/2017	Ordinary Shares	12,583	$ 0	0	D
Incentive Stock Option (right to buy)	$ 7.96	03/21/2013		M			7,040	(3)	05/15/2018	Ordinary Shares	7,040	$ 0	0	D
Incentive Stock Option (right to buy)	$ 1.25	03/21/2013		M			182	(4)	01/20/2019	Ordinary Shares	182	$ 0	0	D
Incentive Stock Option (right to buy)	$ 11.48	03/21/2013		M			2,177	(5)	03/07/2020	Ordinary Shares	2,177	$ 0	15,243	D

Reporting Owners

Reporting Owner Name / Address	Relationships
	Director	10% Owner	Officer	Other
COZADD BRUCE C C/O JAZZ PHARMACEUTICALS PLC CONNAUGHT HOUSE, 1 BURLINGTON RD, FL. 4 DUBLIN 4, L2	X		Chairman and CEO

Signatures

/s/ Larissa Schwartz as attorney in fact for Bruce Cozadd		03/22/2013
**Signature of Reporting Person		Date

Explanation of Responses:

*	If the form is filed by more than one reporting person, see Instruction 4(b)(v).
**	Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1)	This option fully vested on February 18, 2008.
(2)	This option fully vested on February 27, 2012.
(3)	This option fully vested on April 8, 2012.
(4)	This option fully vested on January 21, 2012.
(5)	Following the reported transaction, the remaining ordinary shares subject to this option vest with respect to 6,533 shares in nine equal monthly installments from April 8, 2013 to December 8, 2013 and with respect to 8,710 shares in three equal monthly installments from January 8, 2014 to March 8, 2014.

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