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                                  UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                             WASHINGTON, D.C. 20549

                                    FORM 8-K

                                 CURRENT REPORT
     PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934

                Date of Report (Date of earliest event reported):
                                 March 16, 2006

                               TRANSGENOMIC, INC.
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             (Exact name of registrant as specified in its charter)

       Delaware                      000-30975                 911789357
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(State of Incorporation)     (Commission File Number)        (IRS Employer
                                                         Identification Number)

         12325 Emmet Street, Omaha, Nebraska                      68164
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      (Address of principal executive offices)                 (Zip Code)

                                 (402) 452-5400
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              (Registrant's telephone number, including area code)

                                 Not applicable
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          (Former name or former address, if changed since last report)

Check the appropriate box below if the Form 8-K filing is intended to
simultaneously satisfy the filing obligation of the registrant under any of the
following provisions:

[ ]   Written communications pursuant to Rule 425 under the Securities
      Act (17 CFR 230.425)

[ ]   Soliciting material pursuant to Rule 14a-12 under the Exchange
      Act (17 CFR 240.14a-12)

[ ]   Pre-commencement communications pursuant to Rule 14d-2(b) under the
      Exchange Act (17 CFR 240.14d-2(b))

[ ]   Pre-commencement communications pursuant to Rule 13e-4(c) under the
      Exchange Act (17 CFR 240.13e-4(c))

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ITEM 2.02 RESULTS OF OPERATIONS AND FINANCIAL CONDITION

     On March 16, 2006, Transgenomic, Inc. issued a press release announcing its
financial results for the fourth quarter and fiscal year of 2005. A copy of the
press release is being furnished herewith as Exhibit 99.1 to this Current Report
on Form 8-K.

     The information referenced in this Current Report on Form 8-K (including
Exhibit 99 referenced in Item 9.01 below) is being `furnished" under "Item 2.02.
Results of Operations and Financial Condition" and, as such, shall not be deemed
to be "filed" for the purposes of Section 18 of the Securities Exchange Act of
1934, as amended (the "Exchange Act"), or otherwise subject to the liabilities
of that Section. The information set forth in this Current Report on Form 8-K
(including Exhibit 99 referenced in Item 9.01 below) shall not be incorporated
by reference into any registration statement or other document pursuant to the
Securities Act of 1933, as amended (the "Securities Act"), except as shall be
expressly set forth by specific reference in such filing.

ITEM 9.01. FINANCIAL STATEMENTS AND EXHIBITS.

(d)  Exhibits.

     (99.1)  Press release dated March 16, 2006, announcing Transgenomic,
             Inc.'s financial results for the fourth quarter and fiscal year
             of 2005.

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                                   SIGNATURES

     Pursuant to the requirements of the Securities Exchange Act of 1934, as
amended, the registrant has duly caused this report to be signed on its behalf
by the undersigned hereunto duly authorized.

Dated:  March 16, 2006                      TRANSGENOMIC, INC.

                                            By: /s/ Mitchell L.Murphy
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                                                Mitchell L. Murphy,
                                                VP, Secretary & Treasurer
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