Ownership Submission
FORM 4
Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940
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(Print or Type Responses)
1. Name and Address of Reporting Person *
LEVINE ARNOLD J
  2. Issuer Name and Ticker or Trading Symbol
APPLIED BIOSYSTEMS INC. [ABI]
5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
__X__ Director _____ 10% Owner
_____ Officer (give title below) _____ Other (specify below)
(Last)
(First)
(Middle)
APPLIED BIOSYSTEMS INC., 301 MERRITT 7
3. Date of Earliest Transaction (Month/Day/Year)
11/21/2008
(Street)

NORWALK, CT 06851-1070
4. If Amendment, Date Original Filed(Month/Day/Year)
6. Individual or Joint/Group Filing(Check Applicable Line)
_X_ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person
(City)
(State)
(Zip)
Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security
(Instr. 3)
2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code
(Instr. 8)
4. Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5)
5. Amount of Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 3 and 4)
6. Ownership Form: Direct (D) or Indirect (I)
(Instr. 4)
7. Nature of Indirect Beneficial Ownership
(Instr. 4)
Code V Amount (A) or (D) Price
Applied Biosystems Group Common Stock Units 11/21/2008   D   29,613.49 (1) D (2) 0 D  
Applied Biosystems Group Common Stock 11/21/2008   D   1,200 D (3) 0 D  

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Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security
(Instr. 3)
2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (Month/Day/Year) 3A. Deemed Execution Date, if any (Month/Day/Year) 4. Transaction Code
(Instr. 8)
5. Number of Derivative Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4, and 5)
6. Date Exercisable and Expiration Date
(Month/Day/Year)
7. Title and Amount of Underlying Securities
(Instr. 3 and 4)
8. Price of Derivative Security
(Instr. 5)
9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 4)
10. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 4)
11. Nature of Indirect Beneficial Ownership
(Instr. 4)
Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares
Applied Biosystems Group Director Stock Options-Right to Buy $ 35.7344 (4) 11/21/2008   D     6,000 (4)   (5) 10/21/2009 Applied Biosystems Group Common Stock 6,000 (4) (4) 0 D  
Applied Biosystems Group Director Stock Options-Right to Buy $ 108.3125 (4) 11/21/2008   D     6,000 (4)   (5) 10/19/2010 Applied Biosystems Group Common Stock 6,000 (4) (4) 0 D  
Applied Biosystems Group Director Stock Options-Right to Buy $ 27.975 (4) 11/21/2008   D     8,000 (4)   (5) 10/18/2011 Applied Biosystems Group Common Stock 8,000 (4) (4) 0 D  
Applied Biosystems Group Director Stock Options-Right to Buy $ 20 (4) 11/21/2008   D     8,000 (4)   (5) 10/17/2012 Applied Biosystems Group Common Stock 8,000 (4) (4) 0 D  
Applied Biosystems Group Director Stock Options-Right to Buy $ 23.215 (4) 11/21/2008   D     7,500 (4)   (5) 10/16/2013 Applied Biosystems Group Common Stock 7,500 (4) (4) 0 D  
Applied Biosystems Group Director Stock Options-Right to Buy $ 18.905 (4) 11/21/2008   D     9,200 (4)   (5) 10/21/2014 Applied Biosystems Group Common Stock 9,200 (4) (4) 0 D  
Applied Biosystems Group Director Stock Options-Right to Buy $ 21.2697 (4) 11/21/2008   D     6,000 (4)   (5) 01/21/2009 Applied Biosystems Group Common Stock 6,000 (4) (4) 0 D  
Applied Biosystems Group Director Stock Options-Right to Buy $ 35.985 (4) 11/21/2008   D     9,000 (4)   (5) 10/18/2017 Applied Biosystems Group Common Stock 9,000 (4) (4) 0 D  
Applied Biosystems Group Director Stock Options-Right to Buy $ 23.25 (4) 11/21/2008   D     9,000 (4)   (5) 10/21/2015 Applied Biosystems Group Common Stock 9,000 (4) (4) 0 D  
Applied Biosystems Group Director Stock Options-Right to Buy $ 33.74 (4) 11/21/2008   D     9,000 (4)   (5) 10/20/2016 Applied Biosystems Group Common Stock 9,000 (4) (4) 0 D  

Reporting Owners

Reporting Owner Name / Address Relationships
 Director  10% Owner  Officer  Other
LEVINE ARNOLD J
APPLIED BIOSYSTEMS INC.
301 MERRITT 7
NORWALK, CT 06851-1070
  X      

Signatures

 /s/ Thomas P. Livingston, Attorney-in-Fact for Arnold J. Levine   11/25/2008
**Signature of Reporting Person Date

Explanation of Responses:

* If the form is filed by more than one reporting person, see Instruction 4(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1) Includes 149.37 Applied Biosystems Group Common Stock Units acquired between January and October 2008 pursuant to the dividend reinvestment feature of the Company's director stock purchase and stock incentive plans.
(2) On November 21, 2008, the issuer was acquired by Invitrogen Corporation (renamed Life Technologies Corporation) pursuant to an Agreement and Plan of Merger dated as of June 11, 2008 (as amended, the "merger agreement"). All deferred units for shares of the issuer's Applied Biosystems Group common stock ("ABI stock") held by the reporting person at the time of the merger were assumed by Life Technologies and converted into a right to receive the number of shares of Life Technologies common stock (or an amount in respect thereof for cash-settled deferred units) equal to the number of shares of ABI stock subject to the deferred units held by the reporting person, multiplied by 0.8261, subject to adjustment in accordance with the merger agreement (rounded down to the nearest whole number of shares of Life Technologies common stock).
(3) All shares of ABI stock held by the reporting person at the time of the merger described in Note 2 above were exchanged for merger consideration pursuant to the merger agreement. The merger consideration consists of the right to receive, at the election of each stockholder, either (1) $17.10 in cash and 0.4543 of a share of Life Technologies common stock (plus an additional cash payment of $1.05 per share paid as a merger consideration adjustment due to the trading price of ABI stock during a specified period of time prior to the merger), (2) $38 in cash, or (3) 0.8261 shares of Life Technologies common stock (plus an additional cash payment of $1.91 paid as a merger consideration adjustment due to the trading price of ABI stock during a specified period of time prior to the merger), in the case of (2) and (3) subject to proration in accordance with the merger agreement.
(4) Pursuant to the merger agreement, upon completion of the merger each outstanding award of options to purchase shares of ABI stock was converted into an award to purchase shares of Life Technologies Corporation common stock. Each new stock option award became an award to purchase shares of Life Technologies common stock in an amount equal to the product of (x) 0.8698, multiplied by (y) the number of shares of ABI stock underlying the stock option award outstanding as of closing (rounded down to the nearest share). The exercise price per share of each converted option is equal to the exercise price per share of the option prior to conversion divided by the exchange ratio of 0.8698 (rounded up to the nearest cent).
(5) All of these ABI stock options were fully vested and free from all restrictions upon the completion of the merger described in Note 2 above. Some of the options held by the reporting person and reported in Table II vested at various dates prior to the merger. Pursuant to the merger agreement, options that had not vested prior to the merger became fully vested upon completion of the merger.

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