Ownership Submission
FORM 4
Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940
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(Print or Type Responses)
1. Name and Address of Reporting Person *
Nantucket Investments Ltd
   2. Issuer Name and Ticker or Trading Symbol
Jaguar Health, Inc. [JAGX] 		5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
_____ Director __X__ 10% Owner
_____ Officer (give title below) _____ Other (specify below)
(Last)
(First)
(Middle)
PO BOX 282, REGENCY COURT, GLATEGNY ESPLANADE		 3. Date of Earliest Transaction (Month/Day/Year)
09/25/2018
(Street)

ST PETER PORT, Y7 GY1 3RH		 4. If Amendment, Date Original Filed(Month/Day/Year)
 6. Individual or Joint/Group Filing(Check Applicable Line)
___ Form filed by One Reporting Person
_X_ Form filed by More than One Reporting Person
(City)
(State)
(Zip)
Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security
(Instr. 3)		 2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code
(Instr. 8)		 4. Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5)		 5. Amount of Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 3 and 4)		 6. Ownership Form: Direct (D) or Indirect (I)
(Instr. 4)		 7. Nature of Indirect Beneficial Ownership
(Instr. 4)
Code V Amount (A) or (D) Price
Common Stock 09/25/2018   S   325,615 D $ 1.83 0 D (1)  

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Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security
(Instr. 3)		 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (Month/Day/Year) 3A. Deemed Execution Date, if any (Month/Day/Year) 4. Transaction Code
(Instr. 8)		 5. Number of Derivative Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4, and 5)		 6. Date Exercisable and Expiration Date
(Month/Day/Year)		 7. Title and Amount of Underlying Securities
(Instr. 3 and 4)		 8. Price of Derivative Security
(Instr. 5)		 9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 4)		 10. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 4)		 11. Nature of Indirect Beneficial Ownership
(Instr. 4)
Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares
Non-Voting Common Stock (2) 09/25/2018   S   270,270     (2)   (2) Common Stock 18,019 $ 1.83 38,180,451 D (1)  

Reporting Owners

Reporting Owner Name / Address Relationships
 Director  10% Owner  Officer  Other
Nantucket Investments Ltd
PO BOX 282, REGENCY COURT
GLATEGNY ESPLANADE
ST PETER PORT, Y7 GY1 3RH		     X    
Burford Capital Ltd
PO BOX 282, REGENCY COURT
GLATEGNY ESPLANADE
ST PETER PORT, Y7 GY1 3RH		     X    

Signatures

 NANTUCKET INVESTMENTS LIMITED, By: /s/ Mark Woodall, Title: Director of International Administration Group, as Company Secretary   10/24/2018
**Signature of Reporting Person Date
 BURFORD CAPITAL LIMITED, By: /s/ Mark Woodall, Title: Director of International Administration Group, as Company Secretary   10/24/2018
**Signature of Reporting Person Date

Explanation of Responses:

* If the form is filed by more than one reporting person, see Instruction 4(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1) The securities reported herein are held by Nantucket Investments Limited, a company organized under the laws of Guernsey ("Nantucket"). Burford Capital LLC, a Delaware limited liability company, is the investment adviser to Nantucket. Burford Capital Holdings (UK) Limited, a company organized under the laws of England and Wales, is the sole owner of Burford Capital LLC and is majority owned by Burford Capital Limited, a company organized under the laws of Guernsey and publicly traded on the London Stock Exchange. Each of Nantucket, Burford Capital Limited, Burford Capital LLC and Burford Capital Holdings (UK) Limited disclaim beneficial ownership of the securities listed herein, except to the extent of its respective pecuniary interest therein.
(2) The shares of non-voting common stock are convertible into shares of Common Stock on a one-for-one basis (x) upon transfers to non-affiliates of Nantucket, (y) upon the release from escrow of certain shares of non-voting common stock held by Nantucket to the legacy stockholders of Napo Pharmaceuticals, Inc. under specified conditions and (z) at any time on or after April 1, 2018 at the option of the holder thereof. The shares of non-voting common stock have no expiration date.

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