Ownership Submission
FORM 3
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

INITIAL STATEMENT OF BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940
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(Print or Type Responses)
1. Name and Address of Reporting Person *
  FHM IV LP
2. Date of Event Requiring Statement (Month/Day/Year)
05/30/2007
3. Issuer Name and Ticker or Trading Symbol
AMICUS THERAPEUTICS INC [FOLD]
(Last)
(First)
(Middle)
TWO UNION SQUARE, 601 UNION STREET STE 3200
4. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
_____ Director __X__ 10% Owner
_____ Officer (give title below) _____ Other (specify below)
5. If Amendment, Date Original Filed(Month/Day/Year)
(Street)

SEATTLE, WA 98101
6. Individual or Joint/Group Filing(Check Applicable Line)
___ Form filed by One Reporting Person
_X_ Form filed by More than One Reporting Person
(City)
(State)
(Zip)
Table I - Non-Derivative Securities Beneficially Owned
1.Title of Security
(Instr. 4)
2. Amount of Securities Beneficially Owned
(Instr. 4)
3. Ownership Form: Direct (D) or Indirect (I)
(Instr. 5)
4. Nature of Indirect Beneficial Ownership
(Instr. 5)

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly. SEC 1473 (7-02)
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Table II - Derivative Securities Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security
(Instr. 4)
2. Date Exercisable and Expiration Date
(Month/Day/Year)
3. Title and Amount of Securities Underlying Derivative Security
(Instr. 4)
4. Conversion or Exercise Price of Derivative Security 5. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 5)
6. Nature of Indirect Beneficial Ownership
(Instr. 5)
Date Exercisable Expiration Date Title Amount or Number of Shares
Series B Convertible Preferred Stock   (1)   (1) Common Stock 988,446 $ (1) I (2) By Frazier Healthcare IV, LP
Series B Convertible Preferred Stock   (1)   (1) Common Stock 5,016 $ (1) I (2) By Frazier Affiliates IV, LP
Series C Convertible Preferred stock   (1)   (1) Common Stock 1,011,088 $ (1) I (2) By Frazier Healthcare IV, LP
Series C Convertible Preferred Stock   (1)   (1) Common Stock 5,132 $ (1) I (2) By Frazier Affiliates IV, LP
Series D Convertible Preferred Stock   (1)   (1) Common Stock 572,310 $ (1) I (2) By Frazier Healthcare IV, LP
Series D Convertible Preferred stock   (1)   (1) Common Stock 2,904 $ (1) I (2) By Frazier Affiliates IV, LP
Warrant to purchase Series B (right to buy)   (3)   (3) Series B Convertible Preferred Stock 15,042 $ 6.375 I (2) By Frazier Healthcare IV, LP
Warrant to purchase Series B (right to buy)   (3)   (3) Series B Convertible Preferred Stock 76 $ 6.375 I (2) By Frazier Affiliates IV, LP

Reporting Owners

Reporting Owner Name / Address Relationships
Director 10% Owner Officer Other
FHM IV LP
TWO UNION SQUARE
601 UNION STREET STE 3200
SEATTLE, WA 98101
    X    
FRAZIER HEALTHCARE IV LP

 
    X    
FRAZIER AFFILIATES IV LP

 
    X    

Signatures

FHM IV, LP By: FHM IV, LLC, its General Partner /s/ Thomas S. Hodge, Chief Operating Officer 05/30/2007
**Signature of Reporting Person Date

Explanation of Responses:

* If the form is filed by more than one reporting person, see Instruction 5(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1) The Issuer's Series B, Series C and Series D convertible preferred stock will automatically be converted into Common Stock, 1-for-1, upon the closing of the Issuer's initial public offering.
(2) These securities are owned directly by the entity listed. Frazier Healthcare IV, LP and Frazier Affiliates IV, LP, are joint filers. FHM IV, LP, the designated filer, serves as the general partner of Frazier Healthcare IV, LP and Frazier Affiliates IV, LP. FHM IV, LP disclaims beneficial ownership of the reported securities, except to the extent of its proportionate pecuniary interest therein.
(3) Warrant to purchase Series B convertible preferred stock will automatically be exercised for cash immediately prior to the closing of the Issuer's initial public offering. The Series B shares will automatically be converted to Common Stock upon the closing of the initial public offering.
 
Remarks:
Exhibit 99.1  Joint Filer Information

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