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CUSIP No. |
88078l 10 5 |
1. | NAME OF REPORTING PERSONS I.R.S. Identification No(s). of above person(s) (entities only) MPM BioVentures III, L.P. |
||||
2. | CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (SEE INSTRUCTIONS) |
||||
(a) o | |||||
(b) þ | |||||
3. | SEC USE ONLY | ||||
4. | CITIZENSHIP OR PLACE OF ORGANIZATION | ||||
Delaware | |||||
5. | SOLE VOTING POWER | ||||
NUMBER OF | 383,776 | ||||
SHARES | 6. | SHARED VOTING POWER | |||
BENEFICIALLY | |||||
OWNED BY | 0 | ||||
EACH | 7. | SOLE DISPOSITIVE POWER | |||
REPORTING | |||||
PERSON | 383,776 | ||||
WITH: | 8. | SHARED DISPOSITIVE POWER | |||
0 | |||||
9. | AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON | ||||
383,776 | |||||
10. | CHECK IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES (SEE INSTRUCTIONS) | ||||
o | |||||
11. | PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9) | ||||
0.8% | |||||
12. | TYPE OF REPORTING PERSON (SEE INSTRUCTIONS) | ||||
PN |
Page 2 of 23
CUSIP No. |
88078l 10 5 |
1. | NAME OF REPORTING PERSONS I.R.S. Identification No(s). of above person(s) (entities only) MPM BioVentures III-QP, L.P. |
||||
2. | CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (SEE INSTRUCTIONS) |
||||
(a) o | |||||
(b) þ | |||||
3. | SEC USE ONLY | ||||
4. | CITIZENSHIP OR PLACE OF ORGANIZATION | ||||
Delaware | |||||
5. | SOLE VOTING POWER | ||||
NUMBER OF | 5,707,936 | ||||
SHARES | 6. | SHARED VOTING POWER | |||
BENEFICIALLY | |||||
OWNED BY | 0 | ||||
EACH | 7. | SOLE DISPOSITIVE POWER | |||
REPORTING | |||||
PERSON | 5,707,936 | ||||
WITH: | 8. | SHARED DISPOSITIVE POWER | |||
0 | |||||
9. | AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON | ||||
5,707,936 | |||||
10. | CHECK IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES (SEE INSTRUCTIONS) | ||||
o | |||||
11. | PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9) | ||||
11.1% | |||||
12. | TYPE OF REPORTING PERSON (SEE INSTRUCTIONS) | ||||
PN |
Page 3 of 23
CUSIP No. |
88078l 10 5 |
1. | NAME OF REPORTING PERSONS I.R.S. Identification No(s). of above person(s) (entities only) MPM BioVentures III Parallel Fund, L.P. |
||||
2. | CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (SEE INSTRUCTIONS) |
||||
(a) o | |||||
(b) þ | |||||
3. | SEC USE ONLY | ||||
4. | CITIZENSHIP OR PLACE OF ORGANIZATION | ||||
Delaware | |||||
5. | SOLE VOTING POWER | ||||
NUMBER OF | 172,441 | ||||
SHARES | 6. | SHARED VOTING POWER | |||
BENEFICIALLY | |||||
OWNED BY | 0 | ||||
EACH | 7. | SOLE DISPOSITIVE POWER | |||
REPORTING | |||||
PERSON | 172,441 | ||||
WITH: | 8. | SHARED DISPOSITIVE POWER | |||
0 | |||||
9. | AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON | ||||
172,441 | |||||
10. | CHECK IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES (SEE INSTRUCTIONS) | ||||
o | |||||
11. | PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9) | ||||
0.3% | |||||
12. | TYPE OF REPORTING PERSON (SEE INSTRUCTIONS) | ||||
PN |
Page 4 of 23
CUSIP No. |
88078l 10 5 |
1. | NAME OF REPORTING PERSONS I.R.S. Identification No(s). of above person(s) (entities only) MPM BioVentures III GmbH & Co. Beteiligungs KG |
||||
2. | CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (SEE INSTRUCTIONS) |
||||
(a) o | |||||
(b) þ | |||||
3. | SEC USE ONLY | ||||
4. | CITIZENSHIP OR PLACE OF ORGANIZATION | ||||
Germany | |||||
5. | SOLE VOTING POWER | ||||
NUMBER OF | 482,343 | ||||
SHARES | 6. | SHARED VOTING POWER | |||
BENEFICIALLY | |||||
OWNED BY | 0 | ||||
EACH | 7. | SOLE DISPOSITIVE POWER | |||
REPORTING | |||||
PERSON | 482,343 | ||||
WITH: | 8. | SHARED DISPOSITIVE POWER | |||
0 | |||||
9. | AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON | ||||
482,343 | |||||
10. | CHECK IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES (SEE INSTRUCTIONS) | ||||
o | |||||
11. | PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9) | ||||
0.9% | |||||
12. | TYPE OF REPORTING PERSON (SEE INSTRUCTIONS) | ||||
PN |
Page 5 of 23
CUSIP No. |
88078l 10 5 |
1. | NAME OF REPORTING PERSONS I.R.S. Identification No(s). of above person(s) (entities only) MPM Asset Management Investors 2002 BVIII LLC |
||||
2. | CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (SEE INSTRUCTIONS) |
||||
(a) o | |||||
(b) þ | |||||
3. | SEC USE ONLY | ||||
4. | CITIZENSHIP OR PLACE OF ORGANIZATION | ||||
Delaware | |||||
5. | SOLE VOTING POWER | ||||
NUMBER OF | 112,772 | ||||
SHARES | 6. | SHARED VOTING POWER | |||
BENEFICIALLY | |||||
OWNED BY | 0 | ||||
EACH | 7. | SOLE DISPOSITIVE POWER | |||
REPORTING | |||||
PERSON | 112,772 | ||||
WITH: | 8. | SHARED DISPOSITIVE POWER | |||
0 | |||||
9. | AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON | ||||
112,772 | |||||
10. | CHECK IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES (SEE INSTRUCTIONS) | ||||
o | |||||
11. | PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9) | ||||
0.2% | |||||
12. | TYPE OF REPORTING PERSON (SEE INSTRUCTIONS) | ||||
OO |
Page 6 of 23
CUSIP No. |
88078l 10 5 |
1. | NAME OF REPORTING PERSONS I.R.S. Identification No(s). of above person(s) (entities only) MPM BioVentures III GP, L.P. |
||||
2. | CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (SEE INSTRUCTIONS) |
||||
(a) o | |||||
(b) þ | |||||
3. | SEC USE ONLY | ||||
4. | CITIZENSHIP OR PLACE OF ORGANIZATION | ||||
Delaware | |||||
5. | SOLE VOTING POWER | ||||
NUMBER OF | 0 | ||||
SHARES | 6. | SHARED VOTING POWER | |||
BENEFICIALLY | |||||
OWNED BY | 6,746,496* | ||||
EACH | 7. | SOLE DISPOSITIVE POWER | |||
REPORTING | |||||
PERSON | 0 | ||||
WITH: | 8. | SHARED DISPOSITIVE POWER | |||
6,746,496* | |||||
9. | AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON | ||||
6,746,496* | |||||
10. | CHECK IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES (SEE INSTRUCTIONS) | ||||
o | |||||
11. | PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9) | ||||
13.1% | |||||
12. | TYPE OF REPORTING PERSON (SEE INSTRUCTIONS) | ||||
PN |
Page 7 of 23
CUSIP No. |
88078l 10 5 |
1. | NAME OF REPORTING PERSONS I.R.S. Identification No(s). of above person(s) (entities only) MPM BioVentures III LLC |
||||
2. | CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (SEE INSTRUCTIONS) |
||||
(a) o | |||||
(b) þ | |||||
3. | SEC USE ONLY | ||||
4. | CITIZENSHIP OR PLACE OF ORGANIZATION | ||||
Delaware | |||||
5. | SOLE VOTING POWER | ||||
NUMBER OF | 0 | ||||
SHARES | 6. | SHARED VOTING POWER | |||
BENEFICIALLY | |||||
OWNED BY | 6,746,496* | ||||
EACH | 7. | SOLE DISPOSITIVE POWER | |||
REPORTING | |||||
PERSON | 0 | ||||
WITH: | 8. | SHARED DISPOSITIVE POWER | |||
6,746,496* | |||||
9. | AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON | ||||
6,746,496* | |||||
10. | CHECK IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES (SEE INSTRUCTIONS) | ||||
o | |||||
11. | PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9) | ||||
13.1% | |||||
12. | TYPE OF REPORTING PERSON (SEE INSTRUCTIONS) | ||||
OO |
Page 8 of 23
CUSIP No. |
88078l 10 5 |
1. | NAME OF REPORTING PERSONS I.R.S. Identification No(s). of above person(s) (entities only) Ansbert Gadicke |
||||
2. | CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (SEE INSTRUCTIONS) |
||||
(a) o | |||||
(b) þ | |||||
3. | SEC USE ONLY | ||||
4. | CITIZENSHIP OR PLACE OF ORGANIZATION | ||||
United States | |||||
5. | SOLE VOTING POWER | ||||
NUMBER OF | 0 | ||||
SHARES | 6. | SHARED VOTING POWER | |||
BENEFICIALLY | |||||
OWNED BY | 6,859,268* | ||||
EACH | 7. | SOLE DISPOSITIVE POWER | |||
REPORTING | |||||
PERSON | 0 | ||||
WITH: | 8. | SHARED DISPOSITIVE POWER | |||
6,859,268* | |||||
9. | AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON | ||||
6,859,268* | |||||
10. | CHECK IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES (SEE INSTRUCTIONS) | ||||
o | |||||
11. | PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9) | ||||
13.3% | |||||
12. | TYPE OF REPORTING PERSON (SEE INSTRUCTIONS) | ||||
IN |
Page 9 of 23
CUSIP No. |
88078l 10 5 |
1. | NAME OF REPORTING PERSONS I.R.S. Identification No(s). of above person(s) (entities only) Luke Evnin |
||||
2. | CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (SEE INSTRUCTIONS) |
||||
(a) o | |||||
(b) þ | |||||
3. | SEC USE ONLY | ||||
4. | CITIZENSHIP OR PLACE OF ORGANIZATION | ||||
United States | |||||
5. | SOLE VOTING POWER | ||||
NUMBER OF | 0 | ||||
SHARES | 6. | SHARED VOTING POWER | |||
BENEFICIALLY | |||||
OWNED BY | 6,859,268* | ||||
EACH | 7. | SOLE DISPOSITIVE POWER | |||
REPORTING | |||||
PERSON | 0 | ||||
WITH: | 8. | SHARED DISPOSITIVE POWER | |||
6,859,268* | |||||
9. | AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON | ||||
6,859,268* | |||||
10. | CHECK IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES (SEE INSTRUCTIONS) | ||||
o | |||||
11. | PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9) | ||||
13.3% | |||||
12. | TYPE OF REPORTING PERSON (SEE INSTRUCTIONS) | ||||
IN |
Page 10 of 23
CUSIP No. |
88078l 10 5 |
1. | NAME OF REPORTING PERSONS I.R.S. Identification No(s). of above person(s) (entities only) Nicholas Galakatos |
||||
2. | CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (SEE INSTRUCTIONS) |
||||
(a) o | |||||
(b) þ | |||||
3. | SEC USE ONLY | ||||
4. | CITIZENSHIP OR PLACE OF ORGANIZATION | ||||
United States | |||||
5. | SOLE VOTING POWER | ||||
NUMBER OF | 0 | ||||
SHARES | 6. | SHARED VOTING POWER | |||
BENEFICIALLY | |||||
OWNED BY | 6,859,268* | ||||
EACH | 7. | SOLE DISPOSITIVE POWER | |||
REPORTING | |||||
PERSON | 0 | ||||
WITH: | 8. | SHARED DISPOSITIVE POWER | |||
6,859,268* | |||||
9. | AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON | ||||
6,859,268* | |||||
10. | CHECK IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES (SEE INSTRUCTIONS) | ||||
o | |||||
11. | PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9) | ||||
13.3% | |||||
12. | TYPE OF REPORTING PERSON (SEE INSTRUCTIONS) | ||||
IN |
Page 11 of 23
CUSIP No. |
88078l 10 5 |
1. | NAME OF REPORTING PERSONS I.R.S. Identification No(s). of above person(s) (entities only) Michael Steinmetz |
||||
2. | CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (SEE INSTRUCTIONS) |
||||
(a) o | |||||
(b) þ | |||||
3. | SEC USE ONLY | ||||
4. | CITIZENSHIP OR PLACE OF ORGANIZATION | ||||
United States | |||||
5. | SOLE VOTING POWER | ||||
NUMBER OF | 0 | ||||
SHARES | 6. | SHARED VOTING POWER | |||
BENEFICIALLY | |||||
OWNED BY | 6,859,268* | ||||
EACH | 7. | SOLE DISPOSITIVE POWER | |||
REPORTING | |||||
PERSON | 0 | ||||
WITH: | 8. | SHARED DISPOSITIVE POWER | |||
6,859,268* | |||||
9. | AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON | ||||
6,859,268* | |||||
10. | CHECK IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES (SEE INSTRUCTIONS) | ||||
o | |||||
11. | PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9) | ||||
13.3% | |||||
12. | TYPE OF REPORTING PERSON (SEE INSTRUCTIONS) | ||||
IN |
Page 12 of 23
CUSIP No. |
88078l 10 5 |
1. | NAME OF REPORTING PERSONS I.R.S. Identification No(s). of above person(s) (entities only) Kurt Wheeler |
||||
2. | CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (SEE INSTRUCTIONS) |
||||
(a) o | |||||
(b) þ | |||||
3. | SEC USE ONLY | ||||
4. | CITIZENSHIP OR PLACE OF ORGANIZATION | ||||
United States | |||||
5. | SOLE VOTING POWER | ||||
NUMBER OF | 0 | ||||
SHARES | 6. | SHARED VOTING POWER | |||
BENEFICIALLY | |||||
OWNED BY | 6,859,268* | ||||
EACH | 7. | SOLE DISPOSITIVE POWER | |||
REPORTING | |||||
PERSON | 0 | ||||
WITH: | 8. | SHARED DISPOSITIVE POWER | |||
6,859,268* | |||||
9. | AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON | ||||
6,859,268* | |||||
10. | CHECK IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES (SEE INSTRUCTIONS) | ||||
o | |||||
11. | PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9) | ||||
13.3% | |||||
12. | TYPE OF REPORTING PERSON (SEE INSTRUCTIONS) | ||||
IN |
Page 13 of 23
CUSIP No. |
88078l 10 5 |
1. | NAME OF REPORTING PERSONS I.R.S. Identification No(s). of above person(s) (entities only) Nicholas Simon III |
||||
2. | CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (SEE INSTRUCTIONS) |
||||
(a) o | |||||
(b) þ | |||||
3. | SEC USE ONLY | ||||
4. | CITIZENSHIP OR PLACE OF ORGANIZATION | ||||
United States | |||||
5. | SOLE VOTING POWER | ||||
NUMBER OF | 0 | ||||
SHARES | 6. | SHARED VOTING POWER | |||
BENEFICIALLY | |||||
OWNED BY | 6,859,268* | ||||
EACH | 7. | SOLE DISPOSITIVE POWER | |||
REPORTING | |||||
PERSON | 0 | ||||
WITH: | 8. | SHARED DISPOSITIVE POWER | |||
6,859,268* | |||||
9. | AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON | ||||
6,859,268* | |||||
10. | CHECK IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES (SEE INSTRUCTIONS) | ||||
o | |||||
11. | PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9) | ||||
13.3% | |||||
12. | TYPE OF REPORTING PERSON (SEE INSTRUCTIONS) | ||||
IN |
Page 14 of 23
CUSIP No. |
88078l 10 5 |
1. | NAME OF REPORTING PERSONS I.R.S. Identification No(s). of above person(s) (entities only) Dennis Henner |
||||
2. | CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (SEE INSTRUCTIONS) |
||||
(a) o | |||||
(b) þ | |||||
3. | SEC USE ONLY | ||||
4. | CITIZENSHIP OR PLACE OF ORGANIZATION | ||||
United States | |||||
5. | SOLE VOTING POWER | ||||
NUMBER OF | 45,000* | ||||
SHARES | 6. | SHARED VOTING POWER | |||
BENEFICIALLY | |||||
OWNED BY | 6,859,268** | ||||
EACH | 7. | SOLE DISPOSITIVE POWER | |||
REPORTING | |||||
PERSON | 45,000* | ||||
WITH: | 8. | SHARED DISPOSITIVE POWER | |||
6,859,268** | |||||
9. | AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON | ||||
6,904,268* ** | |||||
10. | CHECK IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES (SEE INSTRUCTIONS) | ||||
o | |||||
11. | PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9) | ||||
13.4% | |||||
12. | TYPE OF REPORTING PERSON (SEE INSTRUCTIONS) | ||||
IN |
Page 15 of 23
(a) | Name of Issuer |
(b) | Address of Issuers Principal Executive Offices |
(a) | Name of Person Filing |
(b) | Address of Principal Business Office or, if none, Residence |
(c) | Citizenship |
(d) | Title of Class of Securities |
(e) | CUSIP Number |
Page 16 of 23
Item 4. Ownership |
MPM BioVentures III, L.P. |
383,776 | |||
MPM BioVentures III-QP, L.P. |
5,707,936 | |||
MPM BioVentures III Parallel Fund, L.P. |
172,441 | |||
MPM BioVentures III GmbH & Co. Beteiligungs KG |
482,343 | |||
MPM Asset Management Investors 2002 BVIII LLC |
112,772 | |||
MPM BioVentures III GP, L.P. |
6,746,496 | (1) | ||
MPM BioVentures III LLC |
6,746,496 | (2) | ||
Ansbert Gadicke |
6,859,268 | (3) | ||
Luke Evnin |
6,859,268 | (3) | ||
Nicholas Galakatos |
6,859,268 | (3) | ||
Michael Steinmetz |
6,859,268 | (3) | ||
Kurt Wheeler |
6,859,268 | (3) | ||
Nicholas Simon III |
6,859,268 | (3) | ||
Dennis Henner |
6,904,268 | (3)(4) |
MPM BioVentures III, L.P. |
0.8 | % | ||
MPM BioVentures III-QP, L.P. |
11.1 | % | ||
MPM BioVentures III Parallel Fund, L.P. |
0.3 | % | ||
MPM BioVentures III GmbH & Co. Beteiligungs KG |
0.9 | % | ||
MPM Asset Management Investors 2002 BVIII LLC |
0.2 | % | ||
MPM BioVentures III GP, L.P. |
13.1 | % | ||
MPM BioVentures III LLC |
13.1 | % | ||
Ansbert Gadicke |
13.3 | % | ||
Luke Evnin |
13.3 | % | ||
Nicholas Galakatos |
13.3 | % | ||
Michael Steinmetz |
13.3 | % | ||
Kurt Wheeler |
13.3 | % | ||
Nicholas Simon III |
13.3 | % | ||
Dennis Henner |
13.4 | % |
MPM BioVentures III, L.P. |
383,776 | |||
MPM BioVentures III-QP, L.P. |
5,707,936 | |||
MPM BioVentures III Parallel Fund, L.P. |
172,441 | |||
MPM BioVentures III GmbH & Co. Beteiligungs KG |
482,343 | |||
MPM Asset Management Investors 2002 BVIII LLC |
112,772 | |||
MPM BioVentures III GP, L.P. |
0 | |||
MPM BioVentures III LLC |
0 | |||
Ansbert Gadicke |
0 |
Page 17 of 23
Luke Evnin |
0 | |||
Nicholas Galakatos |
0 | |||
Michael Steinmetz |
0 | |||
Kurt Wheeler |
0 | |||
Nicholas Simon III |
0 | |||
Dennis Henner |
45,000 | (4) |
MPM BioVentures III, L.P. |
0 | |||
MPM BioVentures III-QP, L.P. |
0 | |||
MPM BioVentures III Parallel Fund, L.P. |
0 | |||
MPM BioVentures III GmbH & Co. Beteiligungs KG |
0 | |||
MPM Asset Management Investors 2002 BVIII LLC |
0 | |||
MPM BioVentures III GP, L.P. |
6,746,496 | (1) | ||
MPM BioVentures III LLC |
6,746,496 | (2) | ||
Ansbert Gadicke |
6,859,268 | (3) | ||
Luke Evnin |
6,859,268 | (3) | ||
Nicholas Galakatos |
6,859,268 | (3) | ||
Michael Steinmetz |
6,859,268 | (3) | ||
Kurt Wheeler |
6,859,268 | (3) | ||
Nicholas Simon III |
6,859,268 | (3) | ||
Dennis Henner |
6,859,268 | (3) |
MPM BioVentures III, L.P. |
383,776 | |||
MPM BioVentures III-QP, L.P. |
5,707,936 | |||
MPM BioVentures III Parallel Fund, L.P. |
172,441 | |||
MPM BioVentures III GmbH & Co. Beteiligungs KG |
482,343 | |||
MPM Asset Management Investors 2002 BVIII LLC |
112,772 | |||
MPM BioVentures III GP, L.P. |
0 | |||
MPM BioVentures III LLC |
0 | |||
Ansbert Gadicke |
0 | |||
Luke Evnin |
0 | |||
Nicholas Galakatos |
0 | |||
Michael Steinmetz |
0 | |||
Kurt Wheeler |
0 | |||
Nicholas Simon III |
0 | |||
Dennis Henner |
45,000 | (4) |
MPM BioVentures III, L.P. |
0 | |||
MPM BioVentures III-QP, L.P. |
0 | |||
MPM BioVentures III Parallel Fund, L.P. |
0 | |||
MPM BioVentures III GmbH & Co. Beteiligungs KG |
0 | |||
MPM Asset Management Investors 2002 BVIII LLC |
0 |
Page 18 of 23
MPM BioVentures III GP, L.P. |
6,746,496 | (1) | ||
MPM BioVentures III LLC |
6,746,496 | (2) | ||
Ansbert Gadicke |
6,859,268 | (3) | ||
Luke Evnin |
6,859,268 | (3) | ||
Nicholas Galakatos |
6,859,268 | (3) | ||
Michael Steinmetz |
6,859,268 | (3) | ||
Kurt Wheeler |
6,859,268 | (3) | ||
Nicholas Simon III |
6,859,268 | (3) | ||
Dennis Henner |
6,859,268 | (3) |
(1) | The shares are held as follows: 5,707,936 by MPM BioVentures III-QP, L.P. (BV III QP), 383,776 by MPM BioVentures III, L.P. (BV III), 172,441 by MPM BioVentures III Parallel Fund, L.P. (BV III PF) and 482,343 by MPM BioVentures III GmbH & Co. Beteiligungs KG (BV III KG). The Reporting Person is the direct general partner of BV III, BV III QP, BV III PF and BV III KG. | |
(2) | The shares are held as follows: 5,707,936 by BV III QP, 383,776 by BV III, 172,441 by BV III PF and 482,343 by BV III KG. The Reporting Person is the indirect general partner of BV III, BV III QP, BV III PF and BV III KG. | |
(3) | The shares are held as follows: 5,707,936 by BV III QP, 383,776 by BV III, 112,772 by MPM Asset Management Investors 2002 BVIII LLC (BV AM LLC), 172,441 by BV III PF and 482,343 by BV III KG. MPM BioVentures III GP, L.P. (BV III GP) and MPM BioVentures III LLC (BV III LLC) are the direct and indirect general partners of BV III, BV III QP, BV III PF and BV III KG. The Reporting Person is a member of BV III LLC and BV AM LLC. The Reporting Person disclaims beneficial ownership of all such shares except to the extent of his proportionate pecuniary interests therein. | |
(4) | Includes 45,000 shares issuable upon exercise of options within 60 days of December 31, 2007. |
Item 5. | Ownership of Five Percent or Less of a Class |
Item 6. | Ownership of More than Five Percent on Behalf of Another Person |
Item 7. | Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on By the Parent Holding Company or Control Person. |
Item 8. | Identification and Classification of Members of the Group |
Item 9. | Notice of Dissolution of a Group |
Item 10. | Certification |
Page 19 of 23
MPM BIOVENTURES III, L.P. | MPM BIOVENTURES III-QP, L.P. | |||||||
By:
|
MPM BioVentures III GP, L.P., | By: | MPM BioVentures III GP, L.P., | |||||
its General Partner | its General Partner | |||||||
By:
|
MPM BioVentures III LLC, | By: | MPM BioVentures III LLC, | |||||
its General Partner | its General Partner | |||||||
By:
|
/s/ Luke Evnin
|
By: | /s/ Luke Evnin
|
|||||
Title: Series A Member | Title: Series A Member | |||||||
MPM BIOVENTURES III PARALLEL FUND, L.P. | MPM BIOVENTURES III GMBH & CO. BETEILIGUNGS KG | |||||||
By:
|
MPM BioVentures III GP, L.P., | By: | MPM BioVentures III GP, L.P., | |||||
its General Partner | in its capacity as the Managing Limited Partner | |||||||
By:
|
MPM BioVentures III LLC, | By: | MPM BioVentures III LLC, | |||||
its General Partner | its General Partner | |||||||
By:
|
/s/ Luke Evnin
|
By: | /s/ Luke Evnin
|
|||||
Title: Series A Member | Title: Series A Member | |||||||
MPM ASSET MANAGEMENT INVESTORS 2002 | MPM BIOVENTURES III GP, L.P. | |||||||
BVIII LLC | By: | MPM BioVentures III LLC, | ||||||
its General Partner | ||||||||
By:
|
/s/ Luke Evnin | |||||||
Name: Luke Evnin Title: Manager |
By: | /s/ Luke Evnin
|
||||||
Title: Series A Member | ||||||||
MPM BIOVENTURES III LLC | ||||||||
By:
|
/s/ Luke Evnin
|
By: | /s/ Ansbert Gadicke
|
|||||
Title: Series A Member | ||||||||
By:
|
/s/ Luke Evnin
|
By: | /s/ Nicholas Galakatos
|
Page 20 of 23
By:
|
/s/ Michael Steinmetz
|
By: | /s/ Kurt Wheeler
|
|||||
By:
|
/s/ Nicholas Simon III | By: | /s/ Dennis Henner | |||||
Name: Nicholas Simon III | Name: Dennis Henner |
Page 21 of 23
MPM BIOVENTURES III, L.P. | MPM BIOVENTURES III-QP, L.P. | |||||||
By:
|
MPM BioVentures III GP, L.P., | By: | MPM BioVentures III GP, L.P., | |||||
its General Partner | its General Partner | |||||||
By:
|
MPM BioVentures III LLC, | By: | MPM BioVentures III LLC, | |||||
its General Partner | its General Partner | |||||||
By:
|
/s/ Luke Evnin
|
By | /s/ Luke Evnin
|
|||||
Title: Series A Member | Title: Series A Member | |||||||
MPM BIOVENTURES III PARALLEL FUND, L.P. | MPM BIOVENTURES III GMBH & CO. BETEILIGUNGS KG | |||||||
By:
|
MPM BioVentures III GP, L.P., | By: | MPM BioVentures III GP, L.P., | |||||
its General Partner | in its capacity as the Managing Limited Partner | |||||||
By:
|
MPM BioVentures III LLC, | By: | MPM BioVentures III LLC, | |||||
its General Partner | its General Partner | |||||||
By:
|
/s/ Luke Evnin
|
By: | /s/ Luke Evnin
|
|||||
Title: Series A Member | Title: Series A Member | |||||||
MPM ASSET MANAGEMENT INVESTORS 2002 | MPM BIOVENTURES III GP, L.P. | |||||||
BVIII LLC | By: | MPM BioVentures III LLC, | ||||||
its General Partner | ||||||||
By:
|
/s/ Luke Evnin | |||||||
Name: Luke Evnin Title: Manager |
By: | /s/ Luke Evnin
|
||||||
Title: Series A Member | ||||||||
MPM BIOVENTURES III LLC | ||||||||
By: Name: |
/s/ Luke Evnin
|
By: | /s/ Ansbert Gadicke
|
|||||
Title:
|
Series A Member |
Page 22 of 23
By:
|
/s/ Luke Evnin
|
By: | /s/ Nicholas Galakatos
|
|||||
By:
|
/s/ Michael Steinmetz
|
By: | /s/ Kurt Wheeler
|
|||||
By:
|
/s/ Nicholas Simon III
|
By: | /s/ Dennis Henner
|
Page 23 of 23